Language of Analytical Chemistry (8L)

1. Satish Pradhan Dnyanasadhana College, Thane.Department of ChemistryM.Sc. Analytical Chemistry Sem-ILanguage of Analytical Chemistry by Dr.G.R.Bhagure

2. Language of Analytical Chemistry (8L) • 1.1.1 Analytical Perspective, Common analytical Problems, terms involved in Analytical Chemistry(analysis, determination, measurement, techniques, methods, procedures and protocol) • 1.1.2 An overview of analytical methods of analytical methods, types of instrumental methods, instruments for analysis, data domains, electrical and non electrical domains, detectors, transducers and sensors, selection of an analytical method, accuracy, precision, selectivity, sensitivity, detection limit and dynamic range

3. 1.1.3 Errors,determinateerrors,and Indeterminate errors,types of determinteerrors,takaling of errors. • 1.1.4 Quntitive methods of analysis: calibration curve, standard addition and internal standard methods

4. 1.2 Quality in Analytical Chemistry (7L) • 1.2.1 Quality Management Systems (QMS) • Evolution and significance of Quality Management Systems , • Types of quality standards for Laboratories, • Total quality management(TQM) • Philosophy implementation of TQM(Reference of Kaizen,six sigma approch & 5S) • Quality Audits &reviews, • Responsibility of Laboratory staff for quality and problems

5. 1.2.2 • Safety in Laboratories • Basic concepts of safety in Laboratories, Personal Protection equipment (PPE) OSHA , • Toxic Hazard(TH) classifications, Hazardous Chemical Processes including (processscalorimetry/thermal build up concepts)

6. 1.2.3 Accreditations • Accreditation of Laboratories, Introduction to ISO series, Indian Government Standard • (ISI, Hallmark, Agmark) • 1.2.4 Good Laboratory Practices (GLP) • Principle,Objective,OECD Guidelines, • The USFDA 21 CFR 58, Klimisch score

16. Physical Change

17. Chemical Change Combustion of Fuel

20. Chemical Methods

21. Chemical Methods

24. Optical Methods

27. Single Beam COLRIMETER Radiation Source Collimating Lens Filter Sample Cell Photocell Read Out Device

28. Radiation Source Collimating Lense O.2 Read out Meter Amplifier PMT Detector Sample Cuvette Grating SINGLE BEAM SPECTROPHOTOMETER

29. PMT Detector Blank Cuvette Mirror Grating Tungsten Lamp Read Out Meter Mirror Sample Cuvette Mirror Deuterium Lamp PMT Detector DOUBLE BEAM SPECTROPHOTOMETER

30. Atomic Absorption Spectrophotometer 62 different metals Rotating Chopper Hollow Cathode Lamp P.M.T.Detector Flame Amplifier Read Out Grating Robert Wilhelm Bunsen and Gustav Robert Kirchhoff, both professors at the University of Heidelberg, Germany. The modern form of AAS 1950s by a team of Australian chemists. They were led by Sir Alan Walsh Power Supply Sample Solution

32. Flame Photometer Na, Mg, K, Li Slit Collimating Mirror P.M.T.Detector Amplifier Read Out Fuel Oxidant Prism Monochromator Sample Solution

33. Plasma Monochromator PMT Detector Amplifier Computer System Read out device system ICPAES SPCTROMETER Nebulizer 60 metals can be determined up to

35. Instrument: Single Beam Fluorimeter Sample Cell U.V. Light & visible light Primary filter Secondary filter Photocell /PMT detector Read Out Device

36. Phosphorimeter • PMT detector Read Out Device

38. Turbidimeter Photocell Detector Read Out Device Sample Cell visible light Filter

39. Nephelometer Graduated Disc Collimating Lens Light Trap visible light Photocell Detector Sample Cell Read Out Device

40. Polarimeter Monochromatic light Analyzer Sample Cell Polarizer Monochromatic light nonlinear

45. Classical Separation Technique

46. Based on Retention capacity of stationary phase

48. TLC: Application of sample and development of Chromatogram by Ascending way High Polar Less Polar

49. ION EXCHANGE CHROMATOGRAPHYH+ Na+ • H+ R

50. ION EXCHANGE CHROMATOGRAPHYH+ Cl- • OH- R