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This study explores the complex interactions between various proteins involved in the translation process within the cytoplasm, focusing on PABP1, eIF4E, TAP, and the role of m7-G RNA. PABP1 and PABP2 are critical in the translation initiation process, while TAP facilitates mRNA export. The research highlights how these proteins interact with RNA elements, including the CTE and RRE, and their implications for HIV Rev function. Understanding these interactions can provide insights into the regulation of gene expression and potential therapeutic targets.
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nucleus cytoplasm PABP1 eIF4E TAP Translation A150 m7-G PABP2 PABP1 CTE eIF4E A150 m7-G PABP2 TAP Translation hRIP, PABP1 Sam68DC RRE eIF4E Crm1, Rev Translation A150 m7-G