Breast Cancer - PowerPoint PPT Presentation

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Breast Cancer
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Breast Cancer

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  1. Breast Cancer

  2. BREAST CANCER • No. 1 in ranking of malignant tumors • 17.50% of total malignancies. American cancer society registry 2006 IC : 15% Insitu: 22% Total breast cancer: 19% DCIS 2% 85% 5.81% 8.42%. 0.17% 0.41% 0.17%

  3. BREAST CANCER • 98.35% were females. • 2.30% < 30 yrs. • Grade II predominated. Histopathological Grading

  4. BREAST CANCER • 69.50% showed LNs. positive for metastasis. • The incidence of lymph node metastasis was slightly higher with IDC (70.25%) versus 62.50% in other types. 66.37% 19.05% 14.58%. Dissected lymph nodes

  5. BREAST CANCER 75%

  6. Hormone receptor status in breast cancer cases +ve -ve 57.80%

  7. Her-2 receptor status in breast cancer cases 55.5% (scores 0 & +1) +++

  8. Time trend for breast cancer in two Pathology Registries % conservative surgery 10% Almost nil

  9. DIGESTIVE SYSTEM MALIGNANT TUMORS • 4thmost common, 13.45% of total malignancy. • A slight male predominance of 54.62% & high adult predominance of 96.59%.

  10. Frequency distribution of Digestive Organ Malignancies 1413 cases 17% 16% 15% 14% 12% 10%

  11. Sites of malignant oral cavity tumors - 241 cases

  12. Histopathologic types of malignant colonic tumors - 223 cases 65.47% 21.52 % Sigmoid colon was the most frequent site involved, represented by 21.63%.

  13. 0.36% of total malignant tumors

  14. RESPIRATORY SYSTEM MALIGNANT TUMORS • 5th most common. • 5.90% of total malignancy. • High male predominance of 73% • High adult predominance 98.62%.

  15. Site distribution of malignant tumors of respiratory organs - 625 cases 16% 28% 13% 24% Malignant lung tumors : pleural mesothelioma ratio 1.8:1.

  16. The male to female ratio was 1.7:1. Histopathologic subtypes of pleural mesothelioma - 82 cases

  17. Histopathologic types of nasopharyngeal malignant tumors -38 cases 39% 47% 8%

  18. FEMALE GENITAL SYSTEM MALIGNANT TUMORS 4.70% of total malignancy. High adult predominance of 97.61%. 36.58% 36.58% 15% 29% Relative frequency of female genital tract malignancies 462 cases .

  19. Histopathologic types of malignant ovarian tumors 135 cases SURFACE EPITHELIAL ORIGIN 73.33% SEX CORD STROMAL ORIGIN GERM CELL ORIGIN

  20. MALIGNANT CNS TUMORS • 0.77% of total malignancy. • A slight adult predominance of 54.44% & no sex predilection (50% each). 67% 13% Central nervous system malignancies – 76 cases

  21. MALIGNANT EYE AND EAR TUMORS • Constituted a minority of 0.16% of total malignancy. Histopathologic types of malignant eye tumors - 14 cases 5 1 4 4 • 2 cases of squamous carcinoma of middle ear.