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This study examines the prevalence of cardiovascular risk factors in very overweight children undergoing a pediatric weight management program. Results show high rates of elevated cholesterol, triglycerides, insulin levels, and other indicators of high cardiovascular risk. Additionally, steatohepatitis was found in a significant number of overweight children. The program also addresses psychosocial factors impacting childhood obesity treatment, with positive outcomes in weight reduction and cardiovascular risk factor improvement seen in the group over nine months.
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High Prevalence of CV Factors in Children seen in a Pediatric Weight Management Program JA Skelton, D Kilway, S Lerret, G Telega • 284 new patients seen over 18 months • Very overweight • BMI Mean = 35 kg/m2 (99.8th percentile) • BMI > 40 = 27% • BMI Range: 17 – 78 kg/m2 • High risk for later CVD • 56% elevated cholesterol • 43% elevated LDL • 14% low HDL • 44% elevated triglycerides • 65% elevated insulin levels
Steatohepatitis in Overweight Children S Lerret, JA Skelton, D Kilway, G Telega • 284 overweight patients (age 2-18 years) • 60 children (21%) demonstrated an elevated ALT • 15 children (5%) demonstrated an elevated AST • 8 children (3%) were biopsied • Mean BMI of patients biopsied = 35.1 (+/- 7.3) • All 8 children had NASH • 7/8 had fibrosis with cirrhosis
Psychosocial factors in a multidisciplinary pediatric obesity treatment programL Miller, JA Skelton, M Otto, J Mao, H Hackbarth, G Flores • 58 patients followed in program for > 9 months • 64% had successful reduction in weight status • Overall group had a reduction in CVRFs • No association with race/ethnicity, income, gender