PITUITARY GLAND. Where is it located??? Name its’ 3 parts or sections. What hormones are secreted by the pituitary gland???. Pituitary Gland. Anterior Pituitary (adenohypophysis). SECRETES 6+ HORMONES: ACTH (adrenocorticotropic hormone) aka (corticotrphin)
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release of cortisol in adrenal glands
release of T3 & T4 in thyroid gland
stimulates growth of bone/tissue
stimulates growth of ovarian follicles & spermatogenesis in males
regulates growth of gonads & reproductive activities
promotes mammary gland growth and milk secretion
i.e. GHRH from hypothalamus
TRH from hypothalamus
(Recall all hormones)
up to 8 ft. tall and > 300 lbs
________ & GH levels.
Avoid bending and straining X 2 months post transsphenoidal hypophysectomy,
Use stool softeners
Saline mouth rinses
No toothbrushes for 7-10 days
any clear rhinorrhea - test for glucose
+ glucose = CSF Leak
HOB 30 degrees
Visual field cuts/diplopia
Post-op complications of hormone deficiency:
What would happen if you didn’t have enough ADH?
What is that disorder called?
functioning hormone levels
What hormones are released by the posterior pituitary?
_____ & _____are released when signaled by hypothalamus
What would the clinical signs/symptoms be?
(too little ADH)
Water deprivation test
>4000ml/24hr ----- fluid restrict at start of test
<4000ml/24hr ---- fluid restrict at midnight
Baseline weight, HR & BP
Hold fluids for 6hrs (usually 6am-12noon)
Hourly urine monitoring for urine SG, osmolality & volume
Draw sample for plasma osmolality when urine osmolality increases <30mOsm/kg
When plasma osmolaity is >288mOsm/kg, pt is deydrated --- admin vasopressin
5 units of Vasopressin (ADH) Subq
Obtain urine osmolality 30-60minutes after injection
Discontinue test if pt weight drops >2kg at any time
Mechanism of action of the paradoxical effect of thiazide diuretics on NDI.
Magaldi A J Nephrol. Dial. Transplant. 2000;15:1903-1905
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