1 / 8

Adrenergic Agonists TUTORIAL

Adrenergic Agonists TUTORIAL. Question 1. For each of the following catecholamines give a short a commentary on their cardiovascular effects after I.V. infusion in humans at therapeutic doses: Norepinephrine Epinephrine Isoprenaline In your comment, state:

joshua-hernandez
Download Presentation

Adrenergic Agonists TUTORIAL

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Adrenergic AgonistsTUTORIAL

  2. Question 1 • For each of the following catecholamines give a short a commentary on their cardiovascular effects after I.V. infusion in humans at therapeutic doses: • Norepinephrine • Epinephrine • Isoprenaline In your comment, state: • Mechanisms of CVS changes as regards sBP, dBP,HR ,and total peripheral resistance. • Effect of pretreatment with an α-blocker in each case.

  3. Question 2 • What are the advantages of the use of Dopamine instead of Norepinephrine in treatment of shock

  4. Question 3 • Both α-1 receptor stimulation and β-2 receptor blockade lower IOP. comment

  5. Question4 • Give two examples for: • Selective α-1- agonists • Selective α-2- agonists • Selective β-1- agonists • Selective β-2- agonists For each of the previous classes, mention two therapeutic uses

  6. CASE

  7. Case history A 6-year- old boy with a history of a mild hay fever, which was treated successfully with OTC medications, had an anaphylactic reaction as a result of a bee sting. In this emergency ,epinephrine 0.3 mg in sterile water was ordered , to be given S.C. By error ,however ,it was given I.V. by a young attending nurse in the E.R.. It resulted in dangerously high blood pressure (180/125 mmHg) and heart rate (125 bpm). The boy was clearly distressed, tense , and frightened. He had fine tremor of the hands, cold clammy skin, and appeared to have a respiratory difficulty.

  8. Questions • Discuss the significance of use of Epinephrine as a drug of choice in anaphylactic shock. • Would Norepinephrine be a suitable choice for the management of anaphylaxis? • Suggest suitable corrective measures to control this crisis

More Related