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Discover the significance and mechanism of DNA replication. Learn why this molecule must replicate, the steps involved, and the roles of DNA helicase, primase, polymerase, and ligase. Explore the continuous synthesis on the leading strand and the formation of Okazaki fragments on the lagging strand.
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Why does this molecule need to be replicated? How will this molecule replicate?
1. DNA helicase unwinds parent strands by breaking hydrogen bonds between the base pairs
2. Primase adds a few RNA nucleotides to DNA template strand
DNA polymerase adds nucleotides to leading strand continuously
DNA polymerase makes Okazaki fragments on the lagging strand and DNA ligase puts them together.