Science Without Borders. Geneticist Dyann Wirth: Understanding the DNA of Parasites. Dyann Wirth Probes Parasites. Geneticist Wirth wants to wipe out malaria by overcoming a parasite’s drug resistance. Plasmodia Are parasitic protozoans Cause malaria Infect humans and mosquitoes.
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Geneticist Dyann Wirth:
Understanding the DNA of Parasites
Geneticist Wirth wants to wipe out malaria by overcoming a parasite’s drug resistance.
How do Plasmodia survive antimalarial medicines?
How can scientists pinpoint what makes Plasmodium falciparum so deadly?
Why do scientists study more than one genome?
Give an example of a SNP.
What is the name for these DNA patterns?
Exploration begins with patient volunteers from malaria clinics on 3 continents
Extract DNA sequences of parasite from blood of volunteers
Recurring SNPs are
promising targets for
vaccines and new drugsWirth’s Experiments
Human activity can spread drug resistance
How do humans help mosquitoes spread resistance across extremely wide geographic areas?
What human-made environments make great breeding sites for mosquito larvae?
Model of Infectious Disease Agent Study
How might knowledge that Wirth and her team have gained about Plasmodium DNA be used to develop an early warning system for malaria drug resistance?