Overview. Herpes Simplex VirusDiseasesHSV EncephalitisDiagnosisTreatmentPrognosisTake Home Points. The Pathogen: Herpes Simplex Virus. Member of family HerpesviridaeHSV-1- tropism for oral mucosa80% of adult population seropositive, though only 30% report clinically significant outbreaksHSV-2- tropism for genital mucosa20% of adult US population is seropositiveOnly 10-20% of those with HSV-2 Abs report a hx of lesionsLarge, enveloped, double stranded-DNA virus.
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