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Organized by Tai-Shan Fang, For Special Advance Physical Organic Chemistry. "click chemistry".
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Organized by Tai-Shan Fang, For Special Advance Physical Organic Chemistry
In the "click chemistry" strategy developed recently at Scripps Research Institute, reactive molecular building blocks are designed to "click" together selectively and covalently. The Scripps researchers are now extending the idea by using protein binding sites, supramolecular complexes, or functionalized surfaces as reaction vessels to direct the in situ formation of potentially functional click chemistry products. The products might be biological inhibitors, molecular-electronics components, sensor probes, nonlinear optical materials, light-harvesting compounds, or compounds with any number of other useful properties.
PERFECT FITModel of acetylcholinesterase inhibitor.
1990- 1994 Researched and wrote Out of Control, the Rise of Neo-Biological Civilization. Reviewed in Fortune magazine as "A book that should be required reading for all executives....As entertaining as it is insightful."
1987 Married Gia-Miin Fuh, a biochemist.
1952 Born, in Pennsylvania, USA
The New Biology of Machines, Social Systems, and the Economic World
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has a chiral centre and was dispensed as a racemate (1:1 mixture) of dextrorotatory (R)- and levorotatory (S)-thalidomide. Initial animal studies indicated that the enantiomers have different biological properties: Calming and sleep-inducing effects are associated with the R-enantiomer, whereas teratogenic effects are more closely associated with the S-enantiomer. Under physiological conditions, both enantiomers undergo rapid interconversion making a total separation of their clinical effects unfeasible.
2001 Nobel Laureate Prof. K. Berry Sharpless visited the Chemistry Department and was conferred an Honorary Doctorate degree from our University on Nov. 17, 2004.(Dec. 10, 2004)