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Analysis of B-cell Labeling in Sheep Infected with BLV Strains over Time

This study investigates the proportion and absolute number of BrdU-labeled B-cells in sheep infected with two strains of Bovine Leukemia Virus (BLV) over a period of days post-infection. We compare the BrdU labeling in BLV-negative (Sheep 4533) and BLV-positive (Sheep 4536) sheep. The data highlights the changes in B-cell populations and their potential implications for understanding the immune response to BLV infection.

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Analysis of B-cell Labeling in Sheep Infected with BLV Strains over Time

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  1. 10 7000 14 6000 12 5000 8 10 4000 8 3000 6 6 2000 4 7000 1000 2 14 4 6000 0 0 12 5000 14 17 21 24 28 31 35 38 42 49 52 58 10 2 4000 8 3000 6 0 2000 4 1000 2 Day 0 Day 24 Day 31 0 0 14 17 21 24 28 31 35 38 42 49 52 58 A. Day 0 Day 24 Day 31 1915 72 1508 66 1721 75 Sheep 4533 BLV- B labeling (PE) 3204 99 3772 385 5067 324 Sheep 4536 BLV+ WT BrdU labeling (FITC) B. Sheep 4533 BLV- Proportion of BrdU-labeled B cells (in %) Sheep 4536 BLV+ WT C. Sheep 4533 BLV- Sheep 4536 BLV+ WT Proportion of BrdU-labeled B cells (in %) Absolute number of B cells (10³/ml) Time post-infection (days) B cells % B+ BrdU+ cells

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