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Peritoneal Scraping with Zy in PDF: Inflammation Study

Study on the effects of Zy administration through PDF on peritoneal scraping cells. Assessing cell infiltration and rASC impact post-ASC.

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Peritoneal Scraping with Zy in PDF: Inflammation Study

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  1. Supplementary Figure 2 Kim H, et al. Group (n) Procedure order Day0 Day 1 Day 2 Day 3 Day 4 Day 5 (A) (B) ASC (-) (9) Peritoneal scraping 5mg of Zy in PDF (ip.) 5mg of Zy in PDF (ip.) 5mg of Zy in PDF (ip.) 5mg of Zy in PDF (ip.) 5mg of Zy in PDF (ip.) 5mg of Zy in PDF (ip.) 5mg of Zy in PDF (ip.) 5mg of Zy in PDF (ip.) 5mg of Zy in PDF (ip.) 5mg of Zy in PDF (ip.) sacrifice (C) (A) Peritoneal scraping 2mL of PBS +8mL of PDF(ip.) 2mL of PBS +8mL of PDF (ip.) 2mL of PBS +3mL of PDF (ip.) 2mL of PBS +8mL of PDF (ip.) (B) post- ASC (+) (9) A (C) Peritoneal thickness sacrifice ns. p< 0.05 (µm) p< 0.05 ns. (/field) (/field) (/field) 1200 Number of total infiltration cells Number of neutrophils 1400 1000 Number of ED-1 positive cells 400 1000 1200 800 800 300 1000 600 600 800 6x106 of rASC in 2mL of PBS + 8mL of PDF (ip.) 6x106 of rASC in 2mL of PBS + 8mL of PDF(ip.) 6x106 of rASC in 2mL of PBS + 8mL of PDF (ip.) 6x106 of rASC in 2mL of PBS + 3mL of PDF (ip.) 200 600 400 400 400 200 100 200 200 0 0 0 0 ASC (–) (n=9) post-ASC (+) (n=9) ASC (–) (n=9) post-ASC (+) (n=9) ASC (–) (n=9) post-ASC (+) (n=9) ASC (–) (n=9) post-ASC (+) (n=9) B C D E

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