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The Prostate Cancer Prevention Trial (PCPT) results indicate the impact of finasteride on biopsy rates and prostate cancer diagnoses. This analysis, presented by Goetzl MA and Holzbeierlein JM (2006), provides crucial insights into how finasteride serves as a chemopreventive agent and its implications for urologic practice. Data reveal significant differences in the number of men undergoing biopsies and subsequently diagnosed with prostate cancer, highlighting finasteride's role in preventive strategies.
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Table 1 Results from the Prostate Cancer Prevention Trial showing the numbers of men who underwent biopsy in each group and the numbers subsequently diagnosed with prostate cancer Goetzl MA and Holzbeierlein JM (2006) Finasteride as a chemopreventive agent in prostate cancer: impact of the PCPT on urologic practice Nat Clin Pract Urol3:422–429 doi:10.1038/ncpuro574