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Explore the effectiveness, risks, and comparison of Double Balloon Endoscopy (DBE) and Capsule Endoscopy (CE) for obscure gastrointestinal bleeding. Discover possible causes, outcomes, and alternative options to diagnose and treat small intestinal bleeding.
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Max Brinsmead MB BS PhD May 2019 Double BALLOON ENDOSCOPY
Problem • 76 year old male Caucasian with significant GIT haemorrhage • No drugs/medication • Colonoscopy and Oesaphogastroduodenoscopy negative • Capsule Endoscopy (CE) GIT • What might it find? • What are the chances it will find something? • What are the other options? • Relative merits of other investigations?
Possible Causes of Small Intestinal Bleeding • Angiodysplasia 50 – 60% • Inflammatory lesions, ulcers and erosions • Includes Crohn’sdisease • Association with NSAID use • More common in Asian series • Polyp (5 – 10%) • Malignancy rare • Includes AdenoCa, Carcinoid and Lymphoma • Diverticula incl. Meckels • Active bleeding without focus
Etiology of obscure gastro-intestinal bleeding according to age
Capsule Endoscopy • Capsule size 26 x 11 mm • Has colour camera, battery, light source and Transmitter • Data recorder worn as a belt • Transit time 24 – 48 hours • Takes 2 images/sec for 8 hours • Will generate 50,000 images • Retention rate 0.4 – 1.4% • Crohn’s is a relative contraindication • Will diagnose a lesion in about 66%
“Double Balloon Something or Other” • What is it? • How successful is it likely to be? • Risks and complications? • Other options?
Double Balloon Endoscopy • Introduced by Yamamoto in 2001 • Allows complete visualization, biopsy and treatment of the small bowel • https://www.youtube.com/watch?v=7LYCtyvgBek
Double Balloon Endoscopy • Essentially 100% successful with no learning curve • 75% antegrade • 25% retrograde • Takes 45 – 90 min • Can biopsy or snare polyps and argon laser angiodysplasia • Best done with CO2 insufflation • Complications more common with diseased bowel e.g Crohns
Meta analysis of Capsule Endoscopy (CE) vs Double Balloon Endoscopy (DBE) • 712 patients in 12 studies • Similar diagnostic yields for both when investigating obscure GIT bleeding • DBE better for diagnosing diverticula • CE better for diagnosing fresh bleeding and clots • They are complimentary modalities • And sometimes simply repeating conventional endoscopy is required
Other Options for Obscure GIT Bleeding • CT and angiography • Single balloon endosocopy • Spiral endoscopy • Operative endoscopy
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