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Human Intervention Required. MB3864A. TM1387. MM4090A. Twinning MM4090A , p21 twinning and space group ambiguities. Real space molecular replacement, combining MR/MAD TM1387 , 2.6 A, 8 mols/asu, homolog to 1n3b; MB3864A , 2.7 A, 3 mols/asu, homolog to 1vpm.

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Human intervention required
Human Intervention Required

MB3864A

TM1387

MM4090A

  • Twinning

  • MM4090A, p21 twinning and space group ambiguities

  • Real space molecular replacement, combining MR/MAD

  • TM1387, 2.6 A, 8 mols/asu, homolog to 1n3b;

  • MB3864A, 2.7 A, 3 mols/asu, homolog to 1vpm

Combining low resolution phases with high resolution data from different crystals

Non-routine NCS averaging

2636534, 4 mols/asu, 2.7 A,

intertwined monomers

2636534

Many heavy atoms

PC06751C, 120 Se,

2.7 A, 6 mols/asu

PC06751C


Number of targets with bound ligands of biological significance: 66

Number of targets containing a UNknown Ligand (UNL): 28

Number of targets containing 2 different ligands of biological significance: 22

FAD or FMN: 3 targets

NAD or NADH: 11 targets

Pyridoxal-5'-Phosphate: 5 targetsATP or ADP: 3 targetsCo-A: 3 targets

S-adenosylmethionine or S-adenosylhomocysteine: 4 targets


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