Hardy-Weinberg Rule

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# Hardy-Weinberg Rule - PowerPoint PPT Presentation

Hardy-Weinberg Rule. Allele frequencies when populations are NOT evolving. Hardy-Weinberg Rule. Allele frequencies will NOT change (stay in equilibrium) if the following conditions are met: No mutation Large population isolated from other populations of same species Random mating

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### Hardy-Weinberg Rule

Allele frequencies when populations are NOT evolving

Hardy-Weinberg Rule
• Allele frequencies will NOT change (stay in equilibrium) if the following conditions are met:
• No mutation
• Large population isolated from other populations of same species
• Random mating
• Individuals survive and reproduce equally
Hardy-Weinberg Rule
• When would we want to know this info?
• It provides a yardstick by which changes in allele frequency can be measured.
• You can see if a population is evolving
Formula for the allele frequency is

p2 + 2pq + q2 = 1

P2 is AA

pq is Aa ( x 2 because aA also)

q2 is aa

You can use the formula to track alleles from one generation to the next to see if the gene frequencies are changing.

p= frequency of allele A

q= frequency of allele a

p+ q = 1

Hardy-Weinberg Rule
Hardy- Weinberg Rule
• If you know the percent of homozygous recessive out of the total population, you know q2. Take the square root of it to find q. q is the frequency of a. Then you can find the rest.