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Hardy Weinberg. Jin Young Huh Joo Hee Kim Sec III. Introduction to Hardy Weinberg . In 1908, G.H. Hardy and W. Weinberg suggested a scheme whereby evolution could be viewed as changes in frequency of alleles in a population of organisms.
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Hardy Weinberg Jin Young Huh Joo Hee Kim Sec III
Introduction to Hardy Weinberg • In 1908, G.H. Hardy and W. Weinberg suggested a scheme whereby evolution could be viewed as changes in frequency of alleles in a population of organisms. • The Hardy-Weinberg model consists of two equations: one that calculates allele frequencies and one that calculates genotype frequencies. • “Allelic frequency will remain same unless acted upon outside force.”
Hardy Equilibrium Equation • p+q=1 • p2+2pq+q2=1
Conditions of Hardy Weinberg Equilibrium • A large breeding population • Mating is random • No mutation • No migration • No selection
Example problem • In lions the allele for the albino trait is recessive over the normal tawny-striped coloration. A sample of 100 wild lions was examined, and it was determined that 9 of these lions were white (aa). How many lions in this population would you expect to be heterozygous for the albino trait? How many homozygous and tawny colored?
Solution • 9/100 = 0.09 of the population is aa (q2) • The square root of 0.09= 0.3 (q) • 1- 0.3 = 0.7 (p) • p2= 0.49 (proportion of the lions that are homozygous dominate) • To get the actual number of lions that are homozygous dominant multiple 0.49 by your total population of 100. 49 lions are tawny and homozygous dominant. • Use 2pq to find the proportion of heterozygous individuals. (2)(0.3)(0.7) = 0.42. 0. 42 out of the 100 lions are heterozygous. • Check your work. 0.09 + 0.49 + 0.42 = 1.
Animation about Hardy Weinberg • http://zoology.okstate.edu/zoo_lrc/biol1114/tutorials/Flash/life4e_15-6-OSU.swf
Sources • LabBench • http://www.phschool.com/science/biology_place/labbench/index.html • Biologycorner • http://www.biologycorner.com/bio4/notes/hardy_weinberg.php • TIEM • http://www.tiem.utk.edu/bioed/bealsmodules/hardy-weinberg.html