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This study focuses on the characterization of recombinant apolipoprotein A-IV (rApo) and its effects when administered in different forms. We examine the impacts of rApo with a molecular weight of 45 kDa, and its variants utilizing methods involving PBS and intravenous administration at a dosage of 0.5 mg. Our analysis covers both the positive (rApo+) and negative (rApo-) variants. The results aim to provide insights into the biological functions and potential therapeutic applications of rApo in lipid metabolism and related disorders.
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Serum BL/6 Apo +/+ BL/6 Apo -/- BL/6 Apo -/- rApo 45kDa 3 2 1 1: rApo 0.5mg iv 2: PBS iv 3: rApo 0.5mg iv rApo, recombinant apolipoprotein A-IV