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ASTRAL cohort. Athens cohort. 1.00. 1.00. 0.75. 0.75. 0.50. 0.50. Sensitivity. Sensitivity. 0.25. 0.25. 0.00. 0.00. 0.00. 0.25. 0.50. 0.75. 1.00. 0.00. 0.25. 0.50. 0.75. 1.00. 1 - Specificity. 1 - Specificity. Area under ROC curve = 0.8502. Area under ROC curve = 0.9371.

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slide1

ASTRAL cohort

Athens cohort

1.00

1.00

0.75

0.75

0.50

0.50

Sensitivity

Sensitivity

0.25

0.25

0.00

0.00

0.00

0.25

0.50

0.75

1.00

0.00

0.25

0.50

0.75

1.00

1 - Specificity

1 - Specificity

Area under ROC curve = 0.8502

Area under ROC curve = 0.9371

Vienna cohort

Athens & Vienna pooled cohort

1.00

1.00

0.75

0.75

0.50

0.50

Sensitivity

Sensitivity

0.25

0.25

0.00

0.00

0.00

0.25

0.50

0.75

1.00

0.00

0.25

0.50

0.75

1.00

1 - Specificity

1 - Specificity

Area under ROC curve = 0.7715

Area under ROC curve = 0.9025

Supplemental figure: Receiver operating characteristics curves (ROC) of the prognostic score in the derivation cohort (upper left figure), in each of the two external validation cohorts (upper right and lower left figure for the Athens and Vienna Stroke cohorts respectively) and in the combination of the external validation cohorts (lower right figure).