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EXPERIMENTAL DESIGN A historical perspective Luc Duchateau Ghent University

EXPERIMENTAL DESIGN A historical perspective Luc Duchateau Ghent University. Experimentation is as old as mankind. Out of Africa Fertile Crescent. First account of “ designed ” experiment. James Lind (1747) Assign treatments in a random way to seamen with scurvey.

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EXPERIMENTAL DESIGN A historical perspective Luc Duchateau Ghent University

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  1. EXPERIMENTAL DESIGNA historicalperspectiveLuc DuchateauGhent University

  2. Experimentation is as old as mankind • Out of Africa • FertileCrescent

  3. First account of “designed” experiment • James Lind (1747) • Assigntreatments in a random way toseamenwithscurvey

  4. Timeline Ethiopia: 1747 • End of golden age of GondarwithLyasu II

  5. First account of randomisationbasedinferenceandoptimal design • Charles Sanders Peirce (1876) • Semiotics

  6. First account of blindedrepeatedmeasures design • Charles Sanders Peirce (1885) • Toassesswhetherthereexists a leastperceptibledifference of excitations • “On small differences in sensation” Memoirs of the NAS 3, 73-83. Subject question: Is W2 smaller or larger than W1? W1 W1 W2

  7. Timeline Ethiopia: 1896 • Battle of Adwa: Menelik II

  8. First account of a collection of experimental designs • Sir Ronald Fischer • Arrangement of field experiments (1926) • Design of experiments (1935) • The geneticaltheory of naturalselection (1930) • Introduction of termssuch as • Blocking • Replication • Orthogonality • Factorial experiments

  9. Timeline Ethiopia: 1931 • EthiopianconstitutionstartedbyEmperorHaileSelassie

  10. First account of fractionalfactoralexperiments in industry • Plackett-Burman designs (1946)

  11. Broaddivision of experimental design • Encyclopedic • Randomised complete block • Latin square • Split plot • Fractional factorial • …. • Optimal • D-optimality • A-optimality …

  12. The future? • Designingsimulationexperiments

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