LEPROSY. EPIDEMIOLOGY. 8 MILLION PATIENTS 60,000 NEW CASES EACH YEAR WORLD WIDE LEPROSY IS ENDEMIC IN ASIA & AFRICA APPOX. 80% CASES IN THESE AREAS IN THE WORLD. Global Leprosy Situation in 2005. WHO Region Point Prevalence
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the morphological index (MI)
the bacteriological index (BI).
PERCENTAGE OF SOLIDLY STAINED BACILLI IN STAINED SMEAR
CMI OR ANTIBODY MEDIATED ?
PCR and recombinant DNA technology
development of gene probes with M leprae–specific sequences.
This technology can be used to identify the mycobacterium in biopsy samples, skin and nasal smears, and blood and tissue sections.
OCCURS IN BORDERLINE CASES NOT IN POLAR LEPROSY