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颅内动脉粥样硬化的影像 2012

颅内动脉粥样硬化的影像 2012. 颅内动脉粥样硬化的影像评估. 1 、对阻塞性血管疾病的诊断(血管腔) 2 、侧枝循环评价 3 、血管壁( HR-MRI ) 4 、血管内流体成分 5 、缺血事件标记物. 趋势: DSA 不作为一线的诊断手段. 金标准 颅内动脉粥样硬化的 DSA : 2% 的神经系统并发症率和 6.1% 的非神经系统并发症率 SAMMPRIS. N Engl J Med. 2011 Sep 15;365(11):993-1003. 侧枝循环都是好事吗?. ANN NEUROL 2011;69:963–974. 看到血管了吗?评价结束了吗?.

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颅内动脉粥样硬化的影像 2012

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  1. 颅内动脉粥样硬化的影像 2012

  2. 颅内动脉粥样硬化的影像评估 1、对阻塞性血管疾病的诊断(血管腔) 2、侧枝循环评价 3、血管壁(HR-MRI) 4、血管内流体成分 5、缺血事件标记物

  3. 趋势:DSA不作为一线的诊断手段 • 金标准 • 颅内动脉粥样硬化的DSA:2%的神经系统并发症率和6.1%的非神经系统并发症率 • SAMMPRIS N Engl J Med. 2011 Sep 15;365(11):993-1003.

  4. 侧枝循环都是好事吗?

  5. ANN NEUROL 2011;69:963–974

  6. 看到血管了吗?评价结束了吗? 提出问题

  7. 最早的大脑中动脉管壁影像研究 W.W.M. Lam Cerebrovasc Dis 2004;17:166–169

  8. 1.5T MRI

  9. 什么是HR-MRI?

  10. 正常管壁 粥样硬化斑块

  11. HR-MRI可靠吗? M-L Li and W-H Xu, et al. Atherosclerosis (2009)

  12. HR-MRI影像与临床的相关性? Xu et al,Atherosclerosis 2010

  13. 症状性狭窄

  14. 无症状性狭窄

  15. Xu et al,Atherosclerosis 2010

  16. 斑块的成分:纤维帽 Xu et al,Atherosclerosis 2010

  17. 斑块的成分:纤维帽 Swartz , et al,ARCH NEUROL 2011

  18. 斑块的成分:出血 Xu el al,ANN NEUROL 2012

  19. Xu el al,ANN NEUROL 2012

  20. 大脑中动脉斑块内出血 Xu el al,ANN NEUROL 2012

  21. 斑块的分布 Xu et al,Stroke 2011

  22. Xu et al,Stroke 2011

  23. Xu et al,Stroke 2011

  24. Xu et al,Stroke 2011

  25. MRI:血栓成分 Liebeskind et al,Stroke. 2011

  26. 微栓子监测

  27. TCD栓子监测:卒中风险的标记物 • CLAIR (Ka Sing Wong等) Wong et al. Lancet Neurol 2010; 9: 489–97

  28. 谢谢!

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