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Auteur : Bruno Flamand, IUT de Dijon

PHYSIOLOGIE DE L'HEMOSTASEEnsemble des diff?rents m?canismes assurant:-la pr?vention des saignements spontan?s-l'arr?t des h?morragies en cas de l?sion vasculaire-le maintien de la fluidit? sanguine-une participation dans les ph?nom?nes de cicatrisation. L'H?mostase: 3 ?tapes inter-d?pend

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Auteur : Bruno Flamand, IUT de Dijon

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    27. * par destruction immunologique : Ac anti-mb PLT ~ Purpura Thrombopénique Auto-Immun –PTAI- : -isolé, considéré comme idiopathique (PTI) ou -associé ŕ MAI, Hémopathie maligne, virus ~ immuno-allergique: HEPARINE, quinine, digitaline, sulfamides, sels d’or, methyldopa… ~ allo-immunisation: (groupes plaquettaires) thrompopénies néonatales (allo-Ac anti-PLT d’origine maternelle) et thrombopénies post-transfusionnelles Ac le + fréquent : anti-HPA1a

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