Edge profile of commercially available square-edge intraocular lenses
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Edge profile of commercially available square-edge intraocular lenses. Mayank A. Nanavaty 1 David J. Spalton 1 James Boyce 2 Anthony Brain 2 John Marshall 2. 1. St. Thomas’ Hospital, London 2. King’s College, London. Financial interests: None. Aim.

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Edge profile of commercially available square edge intraocular lenses

Edge profile of commercially available square-edge intraocular lenses

Mayank A. Nanavaty1 David J. Spalton1 James Boyce2 Anthony Brain2 John Marshall2

1. St. Thomas’ Hospital, London

2. King’s College, London

Financial interests: None


Edge profile of commercially available square edge intraocular lenses

Aim intraocular lenses

To analyze the sharpness of the posterior optic edge of intraocular lenses (IOLs) marketed with a ‘square-edge’ profile.

Methods

  • Seventeen IOLs of different designs and material all marketed as ‘square-edge’ IOLs

  • 20 Diopter IOL of each selected

  • IOLs examined with environmental scanning electron microscopy


Edge profile of commercially available square edge intraocular lenses

FEI Quanta 200F field emission gun environmental scanning electron microscope was used to examine IOLs

  • Parameters standardized for all IOLs

  • 93.3 Pascal (0.7 torr),

  • Specimen temperature of 20oC,

  • Voltage of 15 KV

  • Magnification x 500

  • Average processing time 25 minutes

IOLs mounted using a simple microscope

Haptic excised

Some IOLs required cutting of the

haptic and/or optic to view edge

Posterior edge appears always on the left


Edge profile of commercially available square edge intraocular lenses

Measurement of Radius of Curvature of Posterior Optic Edge electron microscope was used to examine IOLs

Customised computer program measures

the local radius of curvature

L

L

P

P

R

r

R

r

Sharper optic edge = Smaller r

See details in J Cataract Refract Surg, April 2008.


Edge profile of commercially available square edge intraocular lenses

Hydrophobic Acrylic IOLs electron microscope was used to examine IOLs

9.9µ

9.3µ

8.5µ

Alcon

AcrySof IQ

Alcon

AcrySof Natural

Alcon

AcrySof MA60AC


Edge profile of commercially available square edge intraocular lenses

Hydrophobic Acrylic IOLs electron microscope was used to examine IOLs

8.3µ

19.9µ

Hoya AF-1(UY)

AMO Sensar AR40e


Edge profile of commercially available square edge intraocular lenses

Hydrophilic Acrylic IOLs electron microscope was used to examine IOLs

15.9µ

14.3µ

B & L Akreos

B & L MI60

23.1µ

15.5µ

Rayner Superflex

Lenstec Tetraflex


Edge profile of commercially available square edge intraocular lenses

Hydrophilic Acrylic IOLs electron microscope was used to examine IOLs

9.1µ

8.6µ

Human Optics 1CU

Human Optics MC611 MI-B


Edge profile of commercially available square edge intraocular lenses

Silicone IOLs electron microscope was used to examine IOLs

7.6µ

8.3µ

Bausch & Lomb Soflex SE

Bausch & Lomb SofPort AO


Edge profile of commercially available square edge intraocular lenses

Silicone IOLs electron microscope was used to examine IOLs

9.2µ

8.3µ

9.0µ

AMO

Tecnis Z9000

AMO

Clariflex

AMO

Tecnis ZM9000


Edge profile of commercially available square edge intraocular lenses

Summary electron microscope was used to examine IOLs

Radii of curvature (µ)

Hydrophobic Acrylic IOLs

Hydrophilic

Acrylic IOLs

Silicone IOLs


Edge profile of commercially available square edge intraocular lenses

Conclusion electron microscope was used to examine IOLs

  • Commercially marketed ‘square edge’ IOLs differ in posterior edge sharpness.

  • Most hydrophobic acrylic and silicone IOLs have sharper posterior optic square edges compared to most hydrophilic acrylic IOLs. This probably reflects difference in manufacturing techniques.

  • The difference in the posterior optic edge profile may explain why some IOLs have relatively poor PCO performance and may explain why some IOL materials appear to have better PCO performance than others.