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Project 2: Part 1 Technology Development for MR Assessment of Small Animal Physiology Brian Rutt, PhD. MR Gradient Coil Insert Design and Construction Andrew Alejski, PhD Carl Gazdzinski, BSc Yuteng Chen, MSc. 300 mT/m 3-layer rabbit coil (“Rcoil”). Micro-Imaging. 7T, 3D Spin Echo

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slide1

Project 2: Part 1 Technology Development for MR Assessment of Small Animal PhysiologyBrian Rutt, PhD

slide2

MR Gradient Coil Insert Design and ConstructionAndrew Alejski, PhDCarl Gazdzinski, BSc Yuteng Chen, MSc

slide5

Micro-Imaging

7T, 3D Spin Echo

100 micron isotropic

7 hour scan

1.5T, 3D FIESTA

100 micron in-plane

200 micron slices

30 minute scan

next generation insert coil scoil
Next Generation Insert Coil (“Scoil”)
  • 18 cm inner diameter
    • Designed specifically for ultra-high-performance mouse, rat, rabbit imaging using GE Signa Lx and EXCITE at 1.5T and 3T
    • Gmax: 500 mT/m, SlewRate: 2400 T/m/s
  • Completed manufacturing of three identical Scoil prototypes:
    • 1) GE-ASLW / Stanford Research Institute
    • 2) GE-GRC / Albany Medical Center
    • 3) Robarts
slide7

Installation and Early Results from GE-ASLW / SRIYuteng Chen, MScElfar Adalsteinsson, PhDDolf Pfefferbaum, MD

sunday feb 22 2004 cable cutting crimping
Sunday

Feb. 22 2004

Cable cutting & crimping

slide9

Monday

Feb. 23 2004

Twin switch installation

slide10

Monday

Feb. 23 2004

Twin filter installation

slide12

Wednesday

Feb. 25 2004

Insert coil calibration

slide13

Completed / Installed Scoil (3T @ GE-ASLW)

Clinical Insert

Peak gradient 40 mT/m 500 mT/m

Slew rate 150 T/m/s 2000 T/m/s

Resolution 0.8mm 50-100 microns

slide18

Model

Actual

Fig.3 - The electro-thermal circuit

slide20

Temperature sensor: Thermocouples were attached to the hotspot at each wire pattern.

40mm

Cooling tube

Thermocouple

2~2.5mm

1.0mm

Wire pattern

Zigzap cooling line (copper tube) design

slide21

Teflon

tube

Z-axis direction

D

D

Wire pattern

Helical cooling line (Teflon tube) design

concept the harmonic gradient coil

harmonics = winding layers

1

f

(

x

)

a

a

cos(

nx

)

b

sin(

nx

)

=

+

+

o

n

n

2

n

1

n

1

=

=

coefficients = driving currents

Concept: The Harmonic Gradient Coil
  • A multilayered gradient coil with each layer contributing a spatial harmonic of field
  • Drive layers in variable proportions to obtain variable resulting fields/DSVs
  • Amounts to a Fourier Series approximation of the desired field:
slide24

Continuously Variable DSVs

DSV 17cm G= 80 mT/m

DSV 33cm G= 39 mT/m

DSV 48cm G= 29 mT/m

Coil Specs:

ID= 40cm

Inductance= 300 H/layer

Max Current= 300 Amps

Unshielded

conclusions to date
Conclusions To Date
  • High performance insertable gradient coils feasible on clinical 1.5T and 3T GE scanners
  • 10 minute, simple switch-over
  • Performance increase: 10 - 20 fold over best whole-body gradients
  • Spatial resolution < 100µm isotropic
  • Advanced clinical pulse sequences (eg. 3DFIESTA, FSE, DTI) immediately available
  • Advanced hardware (eg. 8-16 fast receivers) immediately available