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(a)

(a). tQ (UUG)H. tE (UUC)E1. SNR30. 500 bp. 500 bp. 500 bp. [0- 1093]. Input. [0- 666]. Sir2. [0- 500]. Hst1. [0- 565]. Sum1. [0- 84]. Hst2. tQ (UUG)H. YHR015W. tE (UUC)E1. YER012W. SNR30. YLR028C. ( b ). tQ (UUG)H. SNR30. Relative IP. Relative IP. Sir2-myc. Sir2-myc.

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(a)

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  1. (a) tQ(UUG)H tE(UUC)E1 SNR30 500 bp 500 bp 500 bp [0- 1093] Input [0- 666] Sir2 [0- 500] Hst1 [0- 565] Sum1 [0- 84] Hst2 tQ(UUG)H YHR015W tE(UUC)E1 YER012W SNR30 YLR028C (b) tQ(UUG)H SNR30 Relative IP Relative IP Sir2-myc Sir2-myc untagged untagged Hst2-myc Hst1-myc Hst2-myc Hst1-myc Sum1-myc Sum1-myc (c) tE(UUC)E1 tQ(UUG)H untagged untagged WT WT sir2∆ sir2∆ hst1∆ hst1∆ sum1∆ sum1∆ Relative IP Relative IP Mcd1-myc Smc4-myc Brn1-myc Mcd1-myc Smc4-myc Brn1-myc

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