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Understanding Lipid Metabolism and Cholesterol Dynamics in Homo sapiens

This overview explores the intricate biochemical pathways involving diacylglycerols, triacylglycerols, and cholesterols within the human body. Key enzymes such as squalene synthetase and lipoprotein lipase play crucial roles in lipid metabolism and cholesterol regulation, including conditions like hypercholesterolemia. Important metabolites like mevalonic acid and Acetoacetyl-CoA are highlighted, along with the functional contributions of apolipoproteins (APOs) and phospholipid transfer proteins in lipid transport to peripheral tissues. Comprehensive insight into these processes is essential for understanding metabolic health.

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Understanding Lipid Metabolism and Cholesterol Dynamics in Homo sapiens

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  1. 1,2-Diacylglycerol HMDB01258 Phospholipid Presqualene diphosphateHMDB01278 Triacylglycerol CholesterolHMDB00067 CholesterolHMDB00067 CholesterolHMDB00067 HYPERCHOSLESTROLEMIA In Homo sapiens Acetoacetyl-CoA HMDB01484 Fatty acid 3-hydroxy- 3-methylglutaryl- coenzyme A reductase P04035 LIVER Mevalonic acidHMDB00227 Cholic Acid HMDB00619 diacylglycerol O-acyltransferase 1 O75907 squalene synthetase P37268 cytochrome P450 7A1 P22680 Cholesterol EsterHMDB06885 squalene monooxygenase Q14534 CholesterolHMDB00067 sterol O-acyltransferase 1 P35610 D D D IDL VLDL lipoprotein lipase P06858 LDL APOAS  hepatic triacylglycerol lipase P11150 APOB APOC2 APOC3  cholesteryl ester transfer protein P11597 APOE HDL phospholipid transfer protein P55058 APOA1 APOC1 APOA4 phosphatidylcholine- sterol acyltransferase P04180 BLOOD PLASMA TO PERIPHERAL TISSUES ATP-binding cassette sub-family A member 1 O95477 Accumulation ENTEROCYTE

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