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Welcome to Prof. Woo Lee’s Lab

Physiological Framework of Microenvironment. Emulsion. Polymer Coating. 1 m m. ECM Protein. Therapeutic Host Defense. ~10 m m RDX+Polymer Microsphere. Osteoblast. S. epidermidis. Yb 2 SiO 5. Substrate. Biomaterial. ~100 nm RDX Nanocrystals. Osteoblast Cells. - - - - -.

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Welcome to Prof. Woo Lee’s Lab

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  1. Physiological Framework of Microenvironment Emulsion Polymer Coating 1 mm ECM Protein Therapeutic Host Defense ~10mm RDX+Polymer Microsphere Osteoblast S. epidermidis Yb2SiO5 Substrate Biomaterial ~100 nm RDX Nanocrystals Osteoblast Cells - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + + + + + “Insensitive 155 Projectile” - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - S. epidermidis Cells Bullet Hole 10 mm 1 mm 100 mm 2mm 10 nm Particle Assembly Viscous/Reactive Sintering SiO2 BaCl2 (aq) (NH4)2SO4 (aq) Nanoparticle Production Yb2O3 Substrate Oil Micromixing Nucleation BaSO4 Nanoparticles Time Diffusion Nanoparticles in Aqueous Droplet Self-Assembled Microspheres Alcohol Negatively Charged Particles Positively Charged Polyelectrolytes • Device Functions • Microfluidic Multiplexing • Nontransparent Biomaterial • Time-lapsed Imaging 2 mm Chemical and Biological Systems of Future Engineered Microenvironment Systems (“Good”) Engineering Flow Nanostructured Surfaces Microstructured Devices $12M Stevens-led teams since 2002 with partners & sponsors New Nanoscale Materials and Phenomena Welcome to Prof. Woo Lee’s Lab Research & Entrepreneurship Day 2008 Nano-Micro-Bio Themes Projects Catalyst Infiltration & Immobilization • Application: On-demand chemical synthesis using micro-structured reactors • Goal: Develop a catalyst coating process to infiltrate and immobilize commercially available catalyst particles • Team: Dr. H. Qiu, Prof. A. Lawal • Funding: DOE, NJCST Nanomaterial Self-Assembly Microfluidics & Microreactors Cell-Biomaterial Interactions High-Temperature Ceramic Coating Tool Box • Application: Next-generation gas turbine components above 1300˚C • Goal: Develop a new Yb2SiO5 coating process for complex shape components • Team: Dr. Y.-F. Su • Funding: ONR Nano-Energetic Materials • Application: RDX nanocrystals for insensitive munitions • Goal: Develop a manufacturing process for producing and coating RDX nanocrystals with reduced safety and health concerns • Team: Dr. Greenberg, Dr. R. Halder, Dr. H. Qiu, Prof. Koven, Prof. Libera from Stevens and V. Stepanov, Dr. P. Anderson, and A. DiStasio from U.S. Army • Funding: ARDEC Confined Self-Assembly Bacteria-Eukaryotic Cell-Biomaterial Interactions • Application: Predictable in vitro infection model for biomedical devices • Goal: Image cell interactions with clinically relevant biomaterial under controlled microenvironment • Team: J.H. Lee, A. Ihnen, T. Boyd (Technogenesis Scholar), Prof. Wang, Prof. Libera • Funding: NSF-NIRT Subgroup Layer-by-Layer Self-Assembly Soft Lithography 2008 ChE Senior Design: Fast-Acting Ibuprofen D. Kandl, M. Abdul-Adziz, M. Muchnik, I. Handel Microfluidic Device Fabrication and Imaging New Jersey Center for MicroChemical Systems Sponsors

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