1 / 4

Locally Advanced Rectal Cancer in IBD Patient: Treatment Insights

Explore a case study of an 83-year-old woman with IBD and rectal adenocarcinoma, discussing treatment options for locally advanced cancer in IBD patients based on clinical trials and research findings.

dionne
Download Presentation

Locally Advanced Rectal Cancer in IBD Patient: Treatment Insights

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Case presented byDr Moriarty • 83 yo woman: PMH – 40 yr h/o IBD on active meds, but non-compliant with f/u colonoscopies • 2010: Increased bleeding and abdominal pressure • PET/CT = tumor from distal sigmoid to anal verge plus deep lymph nodes • Biopsy = adenocarcinoma of the rectum • Consultation to discuss tx for locally advanced rectal CA with known IBD

  2. Phase III Trial Assessing Bevacizumab in Stages II and III Carcinoma of the Colon: Results of NSABP Protocol C-08 Allegra CJ et al. J Clin Oncol 2011; 1(29); 11-16 Lessons From the Adjuvant Bevacizumab Trial on Colon Cancer: What Next? Eric Van Cutsem et al. J Clin Oncol 2011 1(29); 1-4

  3. AVANT: Results from a Randomized, Three-Arm Multinational Phase III Study to Investigate Bevacizumab with Either XELOX or FOLFOX4 vs FOLFOX4 Alone as Adjuvant Treatment for Colon Cancer De Gramont A et al. Proc GICancersSymposium 2011;Abstract 362.

  4. Case presented byDr Moriarty • 83 yo woman: PMH – 40 yr h/o IBD on active meds, but non-compliant with f/u colonoscopies • 2010: Increased bleeding and abdominal pressure • PET/CT = tumor from distal sigmoid to anal verge plus deep lymph nodes • Biopsy = adenocarcinoma of the rectum • Consultation to discuss tx for locally advanced rectal CA with known IBD

More Related