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Understanding Urinary System Functions: Excretion, Metabolic Wastes, and Homeostatic Regulation

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Explore the intricate workings of the urinary system, including excretion of metabolic wastes (urea, creatinine, uric acid), kidney regions, mechanisms of filtration, reabsorption, secretion, and urine concentration regulation.

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Understanding Urinary System Functions: Excretion, Metabolic Wastes, and Homeostatic Regulation

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Presentation Transcript

  1. Urinary System

  2. Functions 1. Excretion • Elimination • Homeostatic Regulation

  3. Metabolic Wastes • Urea • Creatinine • Uric Acid

  4. Urinary System • Kidney regions: • Cortex • Direct filtration • cortical nephrons • juxtamedullarynephrons 2. Medulla • Reabsorption, Secretion • Pelvis excretion

  5. Overview of Urinary System • Flow • Filtration • Reabsorption • Secretion

  6. Glomerular Filtration • Filtration membrane • Net Filtration Pressure: • Glomerular hydrostatic pressure (HPg) (GBHB) • Colloid osmotic pressure (OPg) (BCOP) • Capsular hydrostatic presure (HPg) (CHP) • Glomerular Filtration Rate (GFR)

  7. Tubular Reabsorption • Reabsorption of organic nutrients • Reabsorption of ions, water, and some molecules. • Water reabsorption- osmotic changes due to active transport of sodium ions. • Molecule reabsorption - secondary active transport initiated by ions. Types of Active Transport • Co-transport • Countertransport

  8. Types of carrier mediated transport • Facilitated diffusion • Active Transport (secondary active) • Cotransport(symport) • Countertransport(antiport)

  9. Tubular Secretion • Disposes of unwanted solutes • Regulation of Urine Concentration and Volume • countercurrent mechanism • osmotic gradients • Diuretics

  10. Maintaining Homeostasis Balances: Water/salt pH Blood pressure

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