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Pelotomaculum thermopropionicum SI YP_001212971. Alkaliphilus metalliredigens QYMF YP_001318393. Clostridium phytofermentans ISDg YP_001558292. Clostridium ljungdahlii DSM 13528 YP_003779354. Clostridium novyi NT YP_878968. 70. 53. Clostridium tetani E88 NP_781592.

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Pelotomaculum thermopropionicum SI YP_001212971

Alkaliphilus metalliredigens QYMF YP_001318393

Clostridium phytofermentans ISDg YP_001558292

Clostridium ljungdahlii DSM 13528 YP_003779354

Clostridium novyi NT YP_878968

70

53

Clostridium tetani E88 NP_781592

Clostridium novyi NT YP_878876

59

79

Clostridium novyi NT YP_877304

Clostridium beijerinckii NCIMB 8052 YP_001311126

Oscillibacter valericigenes Sjm18-20 YP_004881457

Shewanella putrefaciens CN-32 YP_001181742

59

Vibrio sp. EJY3 YP_005023151

Pectobacterium wasabiae WPP163 YP_003261426

100

Rhodobacter capsulatus SB 1003 YP_003578336

69

Rhodospirillum rubrum ATCC 11170 YP_426004

83

Rhodopseudomonas palustris BisB18 YP_531058

87

Clostridium botulinum B str. Eklund 17B YP_001885706

Leptotrichia buccalis C-1013-b YP_003164803

86

Sebaldella termitidis ATCC 33386 YP_003307872

84

Enterobacteriaceae bacterium strain FGI 57 YP_007341684

Sebaldella termitidis ATCC 33386 YP_003308725

Vibrio sp. EJY3 YP_005023261

Tolumonas auensis DSM 9187 YP_002893090

90

83

12 Enterobacteria species (BV = 100%)

Spirochaeta smaragdinae DSM 11293 YP_003805842

Parabacteroides distasonis ATCC 8503 YP_001303223

Eubacterium limosum KIST612 YP_003960437

94

Edwardsiella tarda FL6-60 YP_005698020

9 Enterobacteria species (BV = 34%)

52

98

9 Enterobacteria species (BV = 67%)

Pelobacter carbinolicus DSM 2380 YP_006716660

Proteus mirabilis HI4320 YP_002152416

Serratia marcescens FGI94 YP_007343021

Vibrio furnissii NCTC 11218 YP_004991565

53

7 Enterobacteria species (BV = 43%)

81

Desulfitobacterium hafniense Y51 YP_521238

Desulfotomaculum ruminis DSM 2154 YP_004545625

51

Desulfotomaculum reducens MI-1 YP_001114602

86

Desulfosporosinus orientis DSM 765 YP_004973311

Desulfosporosinus meridiei DSM 13257 YP_006624071

Alkaliphilus metalliredigens QYMF YP_001321611

Alkaliphilus oremlandii OhILAs YP_001513925

Clostridium ljungdahlii DSM 13528 YP_003782108

Clostridium phytofermentans ISDg YP_001558532

Clostridium saccharolyticum WM1 YP_003824151

87

Olsenella uli DSM 7084 YP_003800311

Streptococcus intermedius JTH08 YP_006469537

100

Streptococcus dysgalactiae subsp. equisimilis RE378 YP_006860441

Clostridium botulinum F str. Langeland YP_001391411

Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774 YP_002479938

Desulfotalea psychrophila LSv54 YP_065560

Desulfovibrio alaskensis G20 YP_389770

92

Desulfovibrio hydrothermalis AM13 = DSM 14728 YP_007325733

96

Desulfovibrio salexigens DSM 2638 YP_002990075

Desulfovibrio alaskensis G20 YP_389543

Desulfotomaculum kuznetsovii DSM 6115 YP_004517845

Desulfitobacterium dehalogenans ATCC 51507 YP_006428597

Desulfotomaculum ruminis DSM 2154 YP_004544048

Desulfotomaculum reducens MI-1 YP_001114081

90

64

Desulfitobacterium dehalogenans ATCC 51507 YP_006428627

100

Desulfitobacterium hafniense DCB-2 YP_002456870

Desulfitobacterium hafniense Y51 YP_516650

94

Desulfovibrio desulfuricans ND132 YP_005168027

Desulfomicrobium baculatum DSM 4028 YP_003158644

80

56

Desulfotalea psychrophila LSv54 YP_066762

Pectobacterium wasabiae WPP163 YP_003260804

Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774 YP_002480015

Desulfomicrobium baculatum DSM 4028 YP_003158095

94

Desulfovibrio vulgaris str. Hildenborough YP_012037

62

Desulfovibrio alaskensis G20 YP_387768

99

Rhodomicrobium vannielii ATCC 17100 YP_004013872

Alkaliphilus oremlandii OhILAs YP_001514214

Desulfotomaculum ruminis DSM 2154 YP_004545679

79

Clostridium difficile R20291 YP_003217451

84

100

Clostridium kluyveri DSM 555 YP_001396380

99

Alkaliphilus metalliredigens QYMF YP_001319809

Pelobacter carbinolicus DSM 2380 YP_006717121

Desulfovibrio magneticus RS-1 YP_002952805

92

Desulfovibrio hydrothermalis AM13 = DSM 14728 YP_007325494

79

Desulfovibrio salexigens DSM 2638 YP_002991691

99

Clostridium sp. SY8519 YP_004708500

Desulfomonile tiedjei DSM 6799 YP_006447102

Olsenella uli DSM 7084 YP_003800138

Clostridium botulinum BKT015925 YP_004396285

Tannerella forsythia ATCC 43037 YP_005013103

Syntrophobotulus glycolicus DSM 8271 YP_004266818

89

Olsenella uli DSM 7084 YP_003801019

90

Clostridium difficile R20291 YP_003216664

57

Lactobacillus plantarum WCFS1 YP_004890257

Sphaerochaeta coccoides DSM 17374 YP_004410739

88

Olsenella uli DSM 7084 YP_003801189

68

Coriobacterium glomerans PW2 YP_004372167

Sebaldella termitidis ATCC 33386 YP_003309802

52

Melissococcus plutonius ATCC 35311 YP_004455507

Clostridium beijerinckii NCIMB 8052 YP_001307841

51

13 Streptococcus species (BV = 97%)

Acidaminococcus intestini RyC-MR95 YP_004897370

Desulfosporosinus acidiphilus SJ4 YP_006465539

88

Spirochaeta smaragdinae DSM 11293 YP_003801977

Desulfatibacillum alkenivorans AK-01 YP_002431741

Desulfatibacillum alkenivorans AK-01 YP_002429341

Sphaerochaeta coccoides DSM 17374 YP_004410728

Clostridium ljungdahlii DSM 13528 YP_003780757

100

76

Clostridium beijerinckii NCIMB 8052 YP_001307460

Gallionella capsiferriformans ES-2 YP_003847422

Desulfococcus oleovorans Hxd3 YP_001530073

Desulfatibacillum alkenivorans AK-01 YP_002430002

99

Desulfobacula toluolica Tol2 YP_006762114

Desulfomonile tiedjei DSM 6799 YP_006447324

86

Bacteroides fragilis NCTC 9343 YP_213745

Desulfobacterium autotrophicum HRM2 YP_002601708

Halanaerobium hydrogeniformans YP_003994530

Ilyobacter polytropus DSM 2926 YP_003966197

62

Ilyobacter polytropus DSM 2926 YP_003966190

100

Mahella australiensis 50-1 BON YP_004463354

Enterobacter cloacae SCF1 YP_003943560

Treponema azotonutricium ZAS-9 YP_004528865

Syntrophobotulus glycolicus DSM 8271 YP_004266816

Sebaldella termitidis ATCC 33386 YP_003310030

Enterobacter cloacae SCF1 YP_003943814

99

Sebaldella termitidis ATCC 33386 YP_003310469

79

Bacteroides thetaiotaomicron VPI-5482 NP_811868

Coriobacterium glomerans PW2 YP_004372426

Prevotella ruminicola 23 YP_003574839

54

Methanothermobacter thermautotrophicus str. Delta H NP_275488

70

Treponema brennaborense DSM 12168 YP_004438862

55

Methanobacterium formicicum DSM 3637 ZP_11178885

Desulfovibrio vulgaris str. Hildenborough YP_011484

100

Desulfovibrio desulfuricans ND132 YP_005167594

Desulfovibrio salexigens DSM 2638 YP_002993114

63

Acetobacterium woodii DSM 1030 YP_005269165

Desulfitobacterium hafniense Y51 YP_519242

70

Acetobacterium woodii DSM 1030 YP_005269162

74

Desulfobacula toluolica Tol2 YP_006759016

Aromatoleum aromaticum EbN1 YP_158058

100

Geobacter daltonii FRC-32 YP_002537904

99

Geobacter metallireducens GS-15 YP_006720509

Geobacter daltonii FRC-32 YP_002537894

74

Desulfobacula toluolica Tol2 YP_006759356

Desulfatibacillum alkenivorans AK-01 YP_002431362

Desulfobacula toluolica Tol2 YP_006759355

Slackia heliotrinireducens DSM 20476 YP_003144113

Desulfatibacillum alkenivorans AK-01 YP_002431363

100

Desulfatibacillum alkenivorans AK-01 YP_002430893

Archaeoglobus fulgidus DSM 4304 NP_070279

Archaeoglobus sp. PM70-1 AGK61142

100

Natranaerobius thermophilus JW NM-WN-LF YP_001918628

Clostridium difficile R20291 YP_003219619

0.1

Desulfotomaculum ruminis DSM 2154 YP_004544080

88

Clostridium kluyveri DSM 555 YP_001393724

55

Oscillibacter valericigenes Sjm18-20 YP_004883803

57

Desulfotomaculum reducens MI-1 YP_001114294

Desulfosporosinus acidiphilus SJ4 YP_006465540

52

Desulfosporosinus orientis DSM 765 YP_004971939

98

Desulfosporosinus meridiei DSM 13257 YP_006622841

90

Alkaliphilus metalliredigens QYMF YP_001318469

Clostridium botulinum F str. Langeland YP_001392535

Geobacter sulfurreducens PCA NP_953151

Geobacter bemidjiensis Bem YP_002139304

94

Geobacter sp. M18 YP_004199094

99

Thermanaerovibrio acidaminovorans DSM 6589 YP_003317950

Thermovirga lienii DSM 17291 YP_004933394

Odoribacter splanchnicus DSM 20712 YP_004254772

Hippea maritima DSM 10411 YP_004339399

Deferribacter desulfuricans SSM1 YP_003497308

Denitrovibrio acetiphilus DSM 12809 YP_003504240

Coprothermobacter proteolyticus DSM 5265 YP_002247823

Candidatus Korarchaeum cryptofilum OPF8 YP_001736954

Desulfobacterium autotrophicum HRM2 YP_002606146

Desulfomicrobium baculatum DSM 4028 YP_003158861

Parabacteroides distasonis ATCC 8503 YP_001302179

100

70

Bacteroides vulgatus ATCC 8482 YP_001298730

Anaerobaculum mobile DSM 13181 YP_006444861

Thermotoga lettingae TMO YP_001470771

50

Tepidanaerobacter acetatoxydans Re1 YP_007270701

Tepidanaerobacter acetatoxydans Re1 YP_004459566

100

Thermococcus kodakarensis KOD1 YP_182703

53

Aciduliprofundum boonei T469 YP_003482542

Aciduliprofundum sp. MAR08-339 YP_007246921

67

88

Thermococcus sibiricus MM 739 YP_002994043

62

Thermococcus litoralis DSM 5473 ZP_09729921

68