Acute Peripheral Weakness. Peter Shearer, MD Assistant Residency Director Mt. Sinai School of Medicine. Objectives. Acute Extremity Weakness Levels of potential involvement Key Elements of History and Physical for each level CNS PNS Diagnostic Options Therapy. Question #1.
Peter Shearer, MDAssistant Residency DirectorMt. Sinai School of Medicine
At which level of the CNS can a lesion produce motor weakness without affecting mental status?
B. Dorsal root ganglia
C. Spinal Cord
Which of the following can differentiate between acute transverse myelitis and Guillain-Barre Syndrome?
A. ascending vs. descending paralysis
B. presence of slight lymphocytosis in CSF
C. increased vs. decreased reflexes
D. acuity of onset
E. presence of a preceding respiratory or GI illness
Which of the following does NOT produce a myelopathy?
A. Spinal cord infarct
B. Transverse Myelitis
C. Spinal cord metastasis of lung cancer
D. Tick Paralysis
Which of the following illnesses has a well evaluated, prospectively studied therapy?
A. Guillain-Barre Syndrome
B. Acute Transverse Myelitis
C. Acute Spinal Cord Hemorrhage
Can a CNS lesion produce bilateral weakness and sensory deficits and have a normal mental status?