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Weakness. Reduction in the power that can be exerted by one or more muscles.. Weakness . Parts involvedMode of onsetDuration Progression Symmetry . . Is it UMN or LMN ?. UMN . Muscles are involved in groups Weakness of : Shoulder abduction Finger movements Hip flexion Toe do
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1. Approach to Weakness Dr Chaitanya Vemuri
2. Weakness
Reduction in the power that can be exerted by one or more muscles.
3. Weakness Parts involved
Mode of onset
Duration
Progression
Symmetry
4.
Is it UMN or LMN ?
5. UMN Muscles are involved in groups
Weakness of :
Shoulder abduction
Finger movements
Hip flexion
Toe dorsiflexion
Distal muscle groups are affected more than proximal groups
6. UMN Axial muscles are spared unless lesion is bilateral
Rapid repetitive movements are slow but rhythm is preserved
Hypertonia – spastic
Exaggerated tendon reflexes
Loss of abdominal reflexes
Extensor plantar response
No muscle wasting – except disuse atrophy
7. LMN Weakness – in the distribution of lesion in spinal segment, root, nerve
Wasting
Hypotonia
Loss of tendon reflex
Fasiculations of affected muscles
Contracture of muscle
Trophic changes in skin , nail
8. LMN ? Anterior horn cell disease
Spinal root
Peripheral nerve
Neuromuscular Junction
Muscle
9. Ask for symptoms sugg of proximal muscles weakness – upper limb
Unable to comb hair
Not able to take things from height
Not able to hang clothes on cloth lin e
10. Ask for symptoms sugg of distal muscle weakness – upper limb Unable to button shirt
Not able to write
Difficulty in holding things
Cannot open a jar
Cannot close water tap
11. Ask for symptoms sugg of proximal muscle weakness – lower limb Unable to run or hop
Not able to get up from chair / squatting
posture
Not able to climb up stairs ( extensor weakness )
Unable to come down stairs ( quadriceps muscle weakness )
12. Ask for symptoms sugg of distal muscle weakness – lower limb
Tripping on small objects
Dragging of foot while walking
Slipping of chappals with awareness
13. History of neck pain , back pain
History of pain over vertebrae
Are attacks of weakness precipitated by heavy carbohydrate meal ?
Is the weakness precipitated by exposure to cold and exercise ?
Is there weakness of neck muscles ?
14. Are there fasiculations and muscle wasting ?
Is there exercise induced weakness / fatigue with pain ?
Is there weakness and fatiguability after severe exercise ?
Any diurnal variation in weakness ?
15. Any other associated systemic complaints ?
16. Past history Fever prior to weakness
Trauma
Drugs
h/o Tb, DM , HTN, DLP, Cervical spondylosis
CV junction anomaly
17. Family History Similar complaints in family members
Consanguinous marriage
Tuberculosis
Psychiatric illness
Muscular dystrophy
18. Personel history Vaccination prior to onset of weakness
Extramarital contact
Alcohol
Smoking
Drug abuse
19. Thank you