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Welcome to the Bio 181L course! This lab is focused on thinking, understanding, investigating, and evaluating biological concepts, moving beyond memorization. Attendance is crucial, with quizzes and lab assignments playing a significant role in your grade. This course emphasizes observation and reasoning, utilizing hands-on experiments with a strong foundation in chemical principles. Please familiarize yourself with the syllabus and course policies, including strict no-late-work guidelines. Contact the instructor for any absences or personnel inquiries.
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Welcome to 181L • MCB 181L Course Website: http://blc.arizona.edu/courses/181lab • Instructor: Chris Jarchow • Email: christoj@email.arizona.edu • Section: 73 • Office Hour: Tues. 11:00 - noon in Koffler 422 (by appointment only; notify me by Tues. @ 10:50 am) • Email Reading Times: Monday and Wednesday 5-6 pm
181L is … • Thinking, Understanding, Investigating, Evaluating • Not, memorize, regurg., leave, forget, repeat • Manual pp. ix & xi should help • Not sync’ed with most lecture sections, but internally coherent & mutually reinforcing
181 Lab ACCOUNTS • Attendance vs. UAccess.arizona.edu
About You • http://blc.arizona.edu/courses/181lab (Safari home page) • Click ‘Create Accounts’ • Your section number is: ## • **Bio181L_Go** is the way to do your work. Browser bad • Sci. Library, BLC supported • While waiting, fill out a card (name on front; on back, primary concern about this course?).
My Webpage • Get there via homepage* => Instructors => Sxn# *http://blc.arizona.edu/courses/181Lab (Lab Man yellow page)
A few points to discuss • In-class quizzes (every week) • Material from manual • Concepts practiced/demonstrated in class • Primarily covers previous week’s lab • some questions will come from manual on current week’s lab • Course also linked to D2L • ALL written assignments, unless instructed otherwise, will be submitted to the D2L Dropbox (10:00 PM night before lab)
Policies & grading • Syllabus (Linked on course homepage) • Honor code & Plagiarism (Manual, p. xiii) • Assignments • On-line assessments/tutorials (10%) • In-class quizzes (15%) • Lab assignments (LABAs--Lab Activity Based Assignments) (50%) • Lab Projects & reports (combine to 25%) • Every assignment is posted & reported on basis of 100% • For electronic assignments, log in again to see your recorded score • Also reported to you at the end
ATTENTION • No Late Work Accepted! • Absences: must contact Asya Roberts (Bio. East 109) as soon as possible, including planned/unplanned absences • Must be documented as a legitimate excuse (2 absences = dropped) • No dedicated make-up lab available for this course • Late (≥ 10 mins) = absent. leaving early = absent. • Quizzes (in-class) administered at the start of class; MUST be on time to take quiz and receive credit (as well as credit for that day’s assignments)! • Behavior in lab • NO ELECTRONICS, PERIOD. • Beware the admin. drop
How? Why? the Tao of Molecules • How molecules feel & the world they live in
Primary goals • Create understanding by observation, reasoning • Chemical foundations for the course: • Water & its properties • non-watery things • Know molecules as real & tangible things
Atoms • DNA, RNA: C, H, N, O, P, [Mg++] • Carbs: C, H, O • Protein: C, H, N, O, (S), (P), [traces] • Membranes: C, H, N, O, P, (S) *there’s the occasional role for Ca++, etc.
Who am I? • At birth, # protons = # electrons • Atoms seek completion, which means outermost electron set = 8 (hydrogen, helium it’s just 2)
Symbolizing Atoms & Molecules
Views of water H2O
Views of water O H2O H H
Views of water O H2O H H
+ + - Views of water O H2O H H See lab manual, p. 0-3
How to draw molecules Carbon HydrogenOxygenNitrogen Figure is from Lab Manual p. 0-5
Interacting with H2O • To your StructViewers! • Desktop => Bio181L_Go
Hypotheses • What are they?
Hypotheses • Causal explanation of an observed phenomenon
Lab materials • Pipetman operation • Pipet ‘pump’ operation
Tao of Molecules • Group names • Initials of all members (no spaces) • Desktop =>Tao of Molecules
“Salting out” • It’s a real term; used to refer to a situation where the addition of salt (portable charges) alters the solubility of other molecules in water • Why should this be?
Evaporation • First things first--what is it? What’s going on in terms of molecules • Experiment: Ethanol and water on your arm: which is cooler & why? • Prediction: based on molecular weight, which should evaporate more quickly--H2O (2 x 1 + 1 x 16) or CH3CH2OH (5 x 1; 2 x 12; 1 x 16)
Evaporation • If not, why not? • Salt--ever tasted your sweat? Or anybody else’s for that matter? • What benefit might there be to adding NaCl to water that you are intending to evaporate?
Clean up! • Oil waste in the hood • ethanol waste in the sink • anything too messy wadded up and discarded
What’s Assessor? =>Chatting<=
Vocabulary homework • EITHER both versions of the crossword exercise • ORVocabuWary with a better than threshold score • For “Atoms & Molecules”, that’s 60,000 • Errors count off. Slowness counts off.
Homeworkdue 10 p.m. before lab • Assessor: 181 Intro ’12 • Assessor: Molecular World Tutorial • Vocab Atoms/Mols: xWord(x2) or ‘Wary • Next week’s quiz will include: • - Concepts from today • - Atom colors • - Deducing partial charges (from tutorial) • - Manual: Lab 2