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CARDIOVASCULAR DISEASE RISK ASSESSMENT
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  1. CARDIOVASCULAR DISEASE RISK ASSESSMENT

  2. Cardiovascular disease (CVD) Definition • Cardio- = The Heart • -Vascular= Blood Vessels • Cardiovascular diseases = disease of The Heart + Blood vessels

  3. Atherosclerosis

  4. Blood vessels disease can occur everywhere!

  5. STROKE

  6. Coronary Heart Disease

  7. Aortic Aneurysm

  8. Peripheral Artery Disease

  9. Cardiovascular Diseases Stroke Coronary Heart Disease Aortic Aneurysm Peripheral Artery Disease

  10. What is your LIFETIME risk?

  11. Life time risk of Coronary Heart Disease • At 40 years old • 1 in 2 man • 1 in 3 woman Lifetime risk of developing coronary heart disease. Lloyd-Jones DM, Larson MG, Beiser A, Levy D Lancet. 1999;353(9147):89

  12. Already in very high risk • Established cardiovascular disease • Diabetes • Chronic kidney disease

  13. Cardiovascular disease & Diabetes Prediction of Lifetime Risk for Cardiovascular Disease by Risk factor Burden at 50 Years of Age Lloyd-Jones, DM, Leip. EP, Larson, MG et al, Circulation 2006; 113:791

  14. Major risk factors • Increasing age • High cholesterol • High blood pressure • Smoking

  15. Lifetime risk of Cardiovascular disease Risk factors • Cholesterol • BP • Smoking 70% 50% 5% 8% Prediction of Lifetime Risk for Cardiovascular Disease by Risk factor Burden at 50 Years of Age Lloyd-Jones, DM, Leip. EP, Larson, MG et al, Circulation 2006; 113:791

  16. Median survival Risk factors (RF): • BP≥160/100 • Total Cholesterol ≥ 6.2 • Smoking Year

  17. How high is your 10-YEAR risk?

  18. Cardiovascular disease – 10yr risk • The Framingham predictor • http://hp2010.nhlbihin.net/atpiii/calculator.asp?usertype=prof

  19. Calculate the points according to your – Total cholesterol level

  20. Calculate the points according to your - Age

  21. Smoke or not?

  22. “Good cholesterol” (HDL) level ??

  23. Blood pressure??

  24. Get the Sum! -> and your risk

  25. High Cholesterol – treat or not?

  26. Major risk factors • Age (M≥45, F≥55) • Family history of heart attack or sudden death before 55years (M) or 65years (F) • Current cigarette smoking • High blood pressure 140/90mmHg or on treatment • HDL<1.03mmol/L • HDL>1.55mmol/L -> remove one risk factor

  27. High cholesterol – treat or not?

  28. Thank you ; ) Wish you all a health heart

  29. Cardiovascular disease & Blood pressure >160 140-159 130-139 <120 Prediction of Lifetime Risk for Cardiovascular Disease by Risk factor Burden at 50 Years of Age Lloyd-Jones, DM, Leip. EP, Larson, MG et al, Circulation 2006; 113:791

  30. Cardiovascular disease & Total Cholesterol 6.19 5.16-6.18 4.64-5.15 <4.16 Prediction of Lifetime Risk for Cardiovascular Disease by Risk factor Burden at 50 Years of Age Lloyd-Jones, DM, Leip. EP, Larson, MG et al, Circulation 2006; 113:791

  31. Major risk factors • Increasing age • High cholesterol • High “bad cholesterol” (LDL) • Low “good cholesterol” (HDL) • High blood pressure • Smoking • Family history of heart attack or sudden death • … • … • …

  32. Borderline risk factors • Systolic pressure 120 to 139 mmHg • Diastolic pressure 80 to 89 mmHg • LDL-cholesterol 2.6 to 4.1 mmol/L • HDL-cholesterol 1.0 to 1.5 mmol/L • Impaired fasting glucose without overt diabetes • A past history of smoking

  33. Total Chlos >=6.2 • SBP>=160 • DBP>=100 • Smoking • Diabetes • Non-optimal • Total chol 4.65-5.15 • SBP120-139 • DBP80-90