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Cell Cycle Chaos: Understanding Cancer Growth Regulators

Explore the intricate world of cell growth and cancer regulation, from the origin of new cells to the malfunction causing cancer. Learn about DNA structure, cell division signals, and the impact of internal and external regulators on the cell cycle. Discover the causes of cancer, such as smoking, radiation, and viral infections, and the hope for a cure through scientific research. Unveil cancer facts and statistics, including commonly diagnosed cancers in teenagers. Reflect on how our bodies replace cells after injury and the molecules driving cell division and growth.

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Cell Cycle Chaos: Understanding Cancer Growth Regulators

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  1. When Good Cells Go Bad!! Regulators of Cell Growth and Cancer

  2. Standard(s): • BI5. a. Students know the general structures and functions of DNA, RNA, and protein. • Explanation-5.a.-DNA-double helix-contain genetic info, RNA-single-stranded, copy of a section of DNA, protein-make up many parts of the body

  3. Objectives: SWBAT… • Explain the origin of new cells. • Describe the structure and function of DNA. • Understand that cancer is caused by a malfunction of the cell cycle.

  4. Cell Cycle Regulation • Injuries (broken bones and cuts), need new cells • Cells at edge of injury will rapidly divide producing new cells • When the injury heals cell division slows down

  5. Cell Cycle Regulation • What tells cells to divide, make copies of their chromosomes, or enter another phase of the cell cycle? • Many proteins regulate the cell cycle. • Cyclin – causes a mitotic spindle to form in a non-dividing cell. • Internal and External Regulators (proteins)

  6. What is Cancer? • Body’s cells lose the ability to control growth. • Cancer cells do not respond to signals that control cell growth. • Disease of cell cycle. • Tumors (masses of cells)

  7. Causes of Cancer • Causes – smoking tobacco, radiation exposure, and viral infections • Science can lead us to the cure for cancer • Cancer affects all of us

  8. Cancer Factshttp://www.cancer.org/acs/groups/content/@epidemiologysurveilance/documents/document/acspc-029771.pdf • 2011-571,950 expected cancer deaths • Women-over 240,000 women expected to be diagnosed with breast cancer this year • Men-over 240,000 men expected to be diagnosed with prostate cancer this year • Cancers common in teenagers: Ewing’s sarcoma, leukemia, lymphoma, astrocytoma

  9. Lung Cancer Cells

  10. SkinCancer

  11. Breast Cancer Cells

  12. Summary Questions • How does your body replace a cell after an injury? • Which type of molecules tell the cells to divide and grow? • What is cancer? • How can cancer be caused? • Which types of cancer are commonly found in teenagers?

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