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Structural Analysis of Hairpin Arrangements in MVM Replicative DNA Forms

This study investigates the dimer replicative form of the minimal viral model MVM, focusing on junction bridge structures. We analyze the sequence features, including the presence of hairpin arrangements in the Lu.III.Lt-Lt region. The dimerization process is pivotal for viral replication, and the specific arrangements of the A and B arms are crucial for understanding the stability and function of the viral genome. Results reveal insights into the mechanistic roles of specific nucleotide sequences that contribute to the structural integrity of MVM.

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Structural Analysis of Hairpin Arrangements in MVM Replicative DNA Forms

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  1. A. Junction bridge in the dimer replicative form of MVM (28) GA 5’ GAA CT 3’ CTT A arm B arm B. Hairpin arrangements in Lu III Lt-Lt 5’ TC CTC GAG GA 3’ Stuffer 3’ AG GAG CTC CT 5’

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