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DNA Replication. The structure of DNA consists of two polynucleotide strands wrapped around each other in a double helix. 1 chocolate coat, Blind (PRA). Figure 10.3C. Twist. Each base pairs with a complementary partner A pairs with T G pairs with C.

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slide2
The structure of DNA consists of two polynucleotide strands wrapped around each other in a double helix

1 chocolate coat,

Blind (PRA)

Figure 10.3C

Twist

slide3

Each base pairs with a complementary partner

  • A pairs with T
  • G pairs with C
  • Hydrogen bonds between bases hold the strands together
slide4
Three representations of DNA

Hydrogen bond

Ribbon model

Partial chemical structure

Computer model

Figure 10.3D

10 4 dna replication depends on specific base pairing

DNA REPLICATION

10.4 DNA replication depends on specific base pairing
  • In DNA replication, the strands separate
    • Enzymes assemble the new strands
    • With each strand serving as a template

A

A

Nucleotides

Parental moleculeof DNA

Both parental strands serveas templates

Two identical daughtermolecules of DNA

Figure 10.4A

10 5 dna replication a closer look
10.5 DNA replication: A closer look
  • DNA replication begins at specific sites

Parental strand

Origin of replication

Daughter strand

Bubble

Two daughter DNA molecules

Figure 10.5A

slide8

5 end

3 end

P

  • Each strand of the double helix is oriented in the opposite direction

P

P

P

P

P

P

P

3 end

5 end

Figure 10.5B

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3

DNA polymerasemolecule

5

5 end

Daughter strandsynthesizedcontinuously

Parental DNA

5

3

Daughter strandsynthesizedin pieces

  • How DNA daughter strands are synthesized

3

P

5

  • The daughter strands are identical to the parent molecule

5

P

3

DNA ligase

Overall direction of replication

Figure 10.5C