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MR Imaging of the Brain. Radiology 401. John R. Hesselink, M.D. MR System Components. Transmitter. Gradient Amplifier. RF Coil. Gradient. Computer. Gradient. RF Coil. Magnet. Receiver. Digitizer. Source of Signal and Contrast. Proton density T1 relaxation time T2 relaxation time

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mr imaging of the brain
MR Imaging of the Brain

Radiology 401

John R. Hesselink, M.D.

mr system components
MR System Components

Transmitter

Gradient Amplifier

RF Coil

Gradient

Computer

Gradient

RF Coil

Magnet

Receiver

Digitizer

mr imaging

Source of Signal and Contrast

Proton density

T1 relaxation time

T2 relaxation time

Flow effects

MR Imaging
slide4

RF

TR

TE

Signal

Spin-echo Pulse Sequence

Single Echo T1-weighted

1st

echo

2nd

echo

spin echo pulse sequence

RF

TR

TE

TE

Signal

Spin-echo Pulse Sequence

Dual Echo T2-weighted

1st

echo

2nd

echo

slide8

Normal FLAIR Images

TR = 6000 msec, TI = 2000 msec, TE = 102 msec

slide11

T1W

T2W

Solid

Brain

Lesion

PDW

slide12

T1W

Cystic

Lesion

FLAIR

T2W

236

slide13

Subacute

Hemorrhage

PDW

T1W

T2W

slide14

T2W

FLAIR

Acute

Hemorrhage

T1W

GRE

slide16

Hemorrhage Sequence

Gradient-echo

slide17

Fat

or

Lipoma

T2W

PDW

T1W

mr signal intensities
MR Signal Intensities

T2WI

PD/FLAIR

T1WI

Solid mass

Bright

Bright

Dark

Cyst

Bright

Dark

Dark

Subacute blood

Bright

Bright

Bright

Acute & chronic blood

Dark

Dark

Gray

Fat

Dark

Bright

Bright

slide19

Acute Stroke Sequence

Diffusion Weighted Imaging

slide21

MR Spectroscopy

Dx: Anaplastic astrocytoma > GBM

brain screening protocol
Axial T2-weighted images

Axial FLAIR images

If normal:

Stop

If abnormal:

T1-weighted images

Gd-DTPA enhancement

Brain Screening Protocol
slide23

History: 46 y.o. man

with headaches & increasing confusion

2

1

T2W

PDW

slide24

4

3

T1W

T1W

5

{Page 2}

T1W / Gd

slide25

Increasing confusion {Page 3}

6

7

Dx: Meningioma & right MCA infarct