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This physiological CAR consists of an antigen receptor and a CD3ζ intracellular signaling domain with/without a TM and a spacer region, which can also be engineered into immune cells to target its ligands expressed on tumor cells.
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This physiological CAR consists of an antigen receptor and a CD3ζ intracellular signaling domain with/without a TM and a spacer region, which can also be engineered into immune cells to target its ligands expressed on tumor cells. • http://www.creative-biolabs.com/car-t/one-stop-solution-car-development.htm