Synaptic Transmission. Synapse – specialized junction where an axon terminal contacts another neuron or cell type Types of synapses Electrical synapses Chemical synapses
Gray’s type I synapses
Gray’s type II synapses
Synthesis of peptide
Synthesis of amine
and amino acids
ACh and glutamate
Glycine and GABA
-Triggering of an action potential depends on how far the synapse is from the spike initiation zone and the properties of the dendrite (ie. Internal and membrane resistance.)
-Some dendrites have voltage gated channels that can help amplify signals along dendrites.
IPSP are generated when ion channels are opened causing hyperpolarization of the membrane.
Ie. GABA or glycine opens Cl- channels
Shunting Inhibition – inward movement of Cl- anions will negate the flow of positive ions.