Methods for Polymer Microfluidic Fabrication - PowerPoint PPT Presentation

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Methods for Polymer Microfluidic Fabrication
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Methods for Polymer Microfluidic Fabrication

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  1. MIT enterprise forum of washington-baltimore Methods for Polymer Microfluidic Fabrication David Ross, Physicist NIST Gaithersburg, MD www.mitef.org

  2. MIT enterprise forum of washington-baltimore Technology Summary • Polymers for microfluidics • Single-use, disposable • Point-of-care diagnostics • Forensics • In microfluidics, the surface is everything • Sample adsorption • Wetting • Fluid flow • Problem: Polymer surfaces not well controlled www.mitef.org

  3. MIT enterprise forum of washington-baltimore Technology Description • Our technologies: tools for microfluidic polymer fabrication • General-use surface coatings • One step channel fabrication and surface modification • Laser modification of preformed microchannels www.mitef.org

  4. SEM of silicon template Imprinted Plastic Conventional Plastic Fabrication apply pressure heater plastic substrate template heater www.mitef.org

  5. MIT enterprise forum of washington-baltimore - - + + - - - - + + + + - - - - + + - - + + + + - - + + - - + + - - + + - - + + - - + + - - + + - - - - + + - - + + - - + + - - + + - - + + - - + + - - + + - - + + Polyelectrolyte Multilayer Coatings (PEMS) • Alternating layers of charged polymers • Easy, inexpensive • Insensitive to substrate material www.mitef.org

  6. Process gas What is Photoablation? Pulsed UV Laser Focusing optics microchannel plastic programmable motion stage www.mitef.org

  7. Photomodification of preformed microchannel Pulsed UV Laser Focusing optics www.mitef.org

  8. Photomodification for microarrays within channels Protein microarrays within microchannel www.mitef.org

  9. Photopatterning for flow control UV Laser Hydrophilic-Hydrophobic Valve www.mitef.org

  10. MIT enterprise forum of washington-baltimore Current Status • Technical Challenge: Scale-up • Intellectual property: 3 Patents issued (U.S. 6,703,189, 6,860,980, 6,982,028) • Ready for Licensing • Competitors / substitutes • Covalent chemical modification www.mitef.org

  11. MIT enterprise forum of washington-baltimore Contact • For more information: • David Ross • National Institute of Standards and Technology • 301-975-2525 • david.ross@nist.gov • Laurie Locascio • National Institute of Standards and Technology • 301-975-3130 • laurie.locascio@nist.gov www.mitef.org