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Innovative Dry-Powder Inhaler Design for Active Asthma Management

This project focuses on designing a lightweight, single-dose, disposable inhaler specifically for asthmatic individuals. The inhaler aims to provide a rugged, weatherproof alternative to traditional devices, particularly during physical activities and adverse environmental conditions. Utilization of advanced modeling software like SolidWorks allowed for the development and iterative refinement of the prototype, ensuring optimal aerosolization of medication. The team aims to complete the prototype by May 1st, culminating in a final presentation and design report.

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Innovative Dry-Powder Inhaler Design for Active Asthma Management

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  1. Asthma DPI Novel DesignRobert J. TothAnnemarie Alderson, Annie Saha, Stephanie ShaulisTimothy Corcoran, PhD03/29/2005

  2. Project Summary Revisited • To design and develop a dry-powder, single-dose, disposable inhaler • To create a prototype that is self contained, ruggedly constructed, weather and water proof, lightweight, small, ergonomically designed, and actively mobile • To be used by asthmatic individuals that desire a temporary alternative to traditional devices during physical activity and/or in extreme environment settings

  3. Personal Focus Prior Art (All group members) Anthropometric Data (Annie) Drug & Dosage Data (Stephanie) Develop and computationally test a prototype in Solidworks Excipient Data (Myself) Materials Data (Annemarie) Mentor Suggestion/Feedback (Dr. Corcoran)

  4. Prototype Development Iterative Design Process • Create Solid Model • Perform CFD (COSMOS) • Physiologic boundary conditions • Obtain pneumatics within device consistent with 5 m particle aerosolization • Modify/refine the model • Re-perform CFD testing • Continue cycle until acceptable solid model completed

  5. Prototype Development Summary • 9 solid models developed • Initial CFD indicated rotational flow • Inefficient at dispersing and pneumatically transporting micron-sized particles • Due to boundary conditions • Outlet velocity profile v. outlet pressure • Proper boundary conditions implemented • Streamlined flow patterns observed • Model-8 rapid prototyped through Quickparts

  6. Model-2

  7. Model-3

  8. Model-6

  9. Model-7

  10. Model-8

  11. Prototype

  12. Model-9

  13. Tasks to be Completed • Modify physical prototype – Steph will explain why • Modify/Finalize Model-9 • Order second Quickparts prototype • Finish the design report component of the final deliverable document • Collaborate with my teammates on developing the final presentation • Give the presentation • Graduate, May 1st

  14. A Quick Stop Along the Road to Graduation

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