Linkage and Crossing over. Lecture 5 Dr. Attya Bhatti. Linkage. Linkage is defined genetically as the failure of two genes to assort independently. Linkage occurs when two genes are close to each other on the same chromosome.
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Researchers thought that physical coupling between the dominant alleles P and L and between the recessive alleles p and l might have prevented their independent assortment in the F1.
(43 + 22) ÷ 14513 = 1.4 percent.
The two genes T and U are farther apart on a chromosome than V and W. Chromatids cross over between T and U in a larger proportion of meioses than between V and W, so the recombinant frequency for T and U is higher than that for V and W.
The place on the map and on the chromosome where a gene is located is called the gene locus (plural, loci).