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AT Hook Motif

AT Hook Motif. What is it?.

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AT Hook Motif

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  1. AT Hook Motif

  2. What is it? -The AT-hook is a small DNA-binding protein motif-Associated with High Mobility Group (HMG) proteins. Why? -The HMG proteins influence gene transcriptional regulation by participating in the formation of multi-protein complexes on the promoter regions of the genes they regulate.

  3. How does it work? -Peptide Pro-Arg-Lys-Arg-Pro-substrate makes peptide go from disordered to ordered structural transition-crescent shaped backbone -Arganine fits with Adenine

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