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inoculation

Multiplication. Release from macrophages. Transformation. Sand fly. ingestion. inoculation. Vertebrate host. Multiplication and reinfection. Attachment and phagocytosis. Transformation. Leishmania fact sheet. What are Leishmania parasites?.

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inoculation

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  1. Multiplication Release from macrophages Transformation Sand fly ingestion inoculation Vertebrate host Multiplication and reinfection Attachment and phagocytosis Transformation Leishmania fact sheet What are Leishmania parasites? • Protozoan parasites (proto = first; zoan = animal) • Small (usually microscopic) single-celled organisms • Life cycle can be divided into 2 stages depending on the host: • Sand fly vector = Leishmania promastigotes • Human or other vertebrate = Leishmania amastigotes Life cycle of Leishmania parasites Promastigotes Amastigotes Flagellum Leishmania promastigotes Leishmania amastigotes • Form of Leishmania within human or other vertebrate host’s cells (have resorbed their flagellum) • Size: 2-6 mm • Shape: ovoid • Characteristics: central nucleus • Form of Leishmania within sand fly vector: • Can move in the direction of their flagellum • Can be cultured Different parasites cause different forms of the disease Cutaneous lesihmaniasis Visceral lesihmaniasis

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