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Nature's Defense: Fighting Human Disease in Unlikely Places

Explore the incredible abilities of creatures like the Wood Frog to survive freezing temperatures and discover the potential implications for human health. Join our lecture series to delve into this fascinating topic.

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Nature's Defense: Fighting Human Disease in Unlikely Places

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  1. NATURAL ANSWERS / LES SOLUTIONS NATURELLES Defences against human disease in the simplest of places / Des moyens des se défendre contre la maladie humaine trouvés dans les plus simple des lieux MAFA Lunch and Learn Lecture Series Moncton Public Library / Bibliothequepublique de Moncton Christopher Anthony Dieni Margaret and Wallace McCain Postdoctoral Fellow Department of Chemistry and Biochemistry Mount Allison University http://chrisdieni.com

  2. DIABETES / DIABÈTE 9 MILLION CANADIANS / 9 MILLION DE CANADIENS ~25%

  3. Anoxia / Anoxie Hibernation Freezing / Gel Diapause HYPOMETABOLISM / HYPOMÉTABOLISME

  4. WOOD FROG / GRENOUILLE DE BOISRanasylvatica

  5. WOOD FROG / GRENOUILLE DE BOISRanasylvatica

  6. Frogs of various colours are numerous in those parts as far North as the latitude 61°….as the Winter approaches, they burrow under the moss, at a considerable distance from the water, where they remain in a frozen state till the Spring. I have frequently seen them dug up with the moss (when pitching tents in Winter) frozen as hard as ice; in which state the legs are as easily broken off as a pipe-stem, without giving the least sensation to the animal; but by wrapping them up in warm skins, and exposing them to a slow fire, they soon recover life…”.Samuel Hearne A Journey from Prince of Wales’s fort in Hudson’s Bay to the Northern Ocean in the Years 1769-1772

  7. SURVIVING FREEZING / SURVIVRE À LA CONGÉLATION Without protection / Sans protection Unfrozen / Dégelé Ice / Glace Ice / Glace Water / Eau Ice / Glace Freezing / Gel

  8. SURVIVING FREEZING / SURVIVRE À LA CONGÉLATION Without protection / Sans protection Unfrozen / Dégelé Ice / Glace Protein / Protéine Ice / Glace Ice / Glace Water / Eau Ice / Glace Glucose Freezing / Gel With protection / Avec protection

  9. Blood / Sang Liver / Foie Heart / Coeur Kidney / Rein Muscle CRYOPROTECTANTS / CRYOPROTECTEURS Days / Jours Frozen / Gelé Thawed / Dégelé

  10. Blood / Sang Liver / Foie Heart / Coeur Kidney / Rein Muscle CRYOPROTECTANTS / CRYOPROTECTEURS ~50 times normal blood glucose within 3 days of freezing / ~ 50 fois la glycémie normale en 3 jours de gel Days / Jours Frozen / Gelé Thawed / Dégelé

  11. Blood / Sang Liver / Foie Heart / Coeur Kidney / Rein Muscle CRYOPROTECTANTS / CRYOPROTECTEURS Normal blood glucose within less than 2 weeks of thawing / ~ Glycémie normale en moins de 2 semaines de dégel Days / Jours Frozen / Gelé Thawed / Dégelé

  12. Anoxia / Anoxie Hibernation Freezing / Gel Diapause HYPOMETABOLISM / HYPOMÉTABOLISME

  13. THE FUTURE? / LE FUTUR?

  14. THANK YOU! / MERCI! http://chrisdieni.com http://twitter.com/chrisdieni

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