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P-STAT2

A. B. P117. WT. Genomic sequence. cDNA sequence (P117). IFN a 3 h 6h. IFN g 0 3 h 6h. IFN a 3 h 6h. IFN g 0 3 h 6h. P117. WT. Exon 4. Exon 5. P-STAT1. STAT1. P-STAT2. STAT2. P-STAT3. STAT3.

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P-STAT2

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  1. A. B. P117 WT Genomic sequence cDNA sequence (P117) IFNa 3h6h IFNg 0 3h 6h IFNa 3h6h IFNg0 3h 6h P117 WT Exon 4 Exon 5 P-STAT1 STAT1 P-STAT2 STAT2 P-STAT3 STAT3 1 138 315 570 708 923 b-actin SH2 PI DBD Coiled-coil TAD SH2 C. WT STAT2m/m(P117) IFNa 0 3 6 h (X10-3) 0.12 2.5 WT 2.0 0.10 ST2 m/+ 1.5 1.0 ST2 m/m (P117) 0.08 0.5 0 Relative mRNA 0 h 3 h 6 h 0.06 0.04 0.02 0 0 h 3 h 6 h ST2

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