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How should be the therapeutical approach to COPD patient?. Nikos Siafakas MD, PhD, FCCP Professor of Thoracic Medicine University of Crete, Greece President of ERS 2009-2010 TTC April 2009. Before starting the therapeutic approach we need.
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How should be the therapeutical approach to COPD patient? Nikos Siafakas MD, PhD, FCCP Professor of Thoracic Medicine University of Crete, Greece President of ERS 2009-2010 TTC April 2009
Before starting the therapeutic approach we need • Proper Diagnosis (Differential Diagnosis) • Staging of Severity of Disease
Proper diagnosis • History (Smoking environmental/exposure) b. Symptoms (cough, phlegm, dyspnea) c. SPIROMETRY
Severity of disease Spirometric staging [FEV1] ATS/ERS stages of severity
Non-pharmacological interventions in COPD • Smoking cessation • Mechanical ventilation • Surgery for COPD • Rehabilitation • LTOT ????
Management of Stable COPD Reduce Risk Factors: Smoking Cessation • Counseling delivered by physicians and other health professionals significantly increases quit rates over self-initiated strategies. Even a brief (3-minute) period of counseling to urge a smoker to quit results in smoking cessation rates of 5-10%. .
Co-morbidities COPD has significant extrapulmonary (systemic) effects including: Weight loss Nutritional abnormalities Skeletal muscle dysfunction
Vicious circle of COPD lack of exercise COPD Dyspnea immobility (deconditioning) Depression social isolation
Pulmonary RehabilitationDefinition • PUL-REHAB is a multidisciplinary program of care for patients with COPD that is individually tailored and designed to optimize physical and social performance and autonomy
Pulmonary rehabilitation: multidisciplinary • Exercise training • Nutrition interventions • Sleep interventions • Education • Psychological and social considerations
Rehabilitation: Exercise • Bicycle ergometer • Treadmill • Walking (6-20 min) • Upper limbs • Respiratory muscles (insp/exp) • Others (NMES)
Pulmonary Rehabilitation • COPD of all stages benefit from exercise training programs • Minimum duration at least 4 weeks (best 4-10 weeks) • Benefits wane after the end but sustained above pre –rehab levels for long time (even a year) • Repeated or home training sustain benefits
Nutrition • Assess : • BMI less than 21 Kg/m2 underweighted • BMI : 25-30 Kg/m2 over weighted • BMI more than 30 Kg/m2 obese • Estimation of weight loss: • more than 10% last 6 months or 5% the • last month
Nutrition • Nutritional interventions are effective in combination with exercise and/or other anabolic stimuli
Interventions during SLEEP • In COPD sleep is significantly impaired a) as part of the course of the disease ( marked desaturation) • b) co-existing sleep apnea syndromes • CPAP or O2 improves QoL
Education: topics • Breathing strategies • Proper use of medications/O2 • Bronchial hygiene • Benefits of physical activities • Energy conservation techniques • Nutritional strategies • Prevention and copying with exacerbations • Travel leisure sexuality • End-of-life planning • Anxiety stress and panic management /relaxation techniques
ATS/ERS statement : concluded ARRDCC 2006:173.1390-1413 • Pul- rehab must be available to all COPD patients who need it • More research is needed to optimize effectiveness • Develop better ways to maintain benefits • Evaluate the effects of REHAB on SURVIVAL
Meta-analysis :Lancet 1996Cochrane database 2002 • Rehab relieves dyspnea , fatigue and enchances patient’s sense of control over their condition. Although the average improvement in exercise was modest. Rehab forms an important component of the management of COPD
Pulmonary Rehabilitation: is cost effective ? • British study shows that Rehab is effective to reduce overall cost in health services • Canadian study =cost is 11597 CDN /person
Effects of Home-based Pul-Rehab in COPD • Canadian study: Maltais et al: Ann Inter Med 2008 (16) 869-78 • Home rehab is a useful equivalent alternative to outpatient rehab in COPD
CONCLUSION • In COPD the non-Pharmacological interventions are at least as important and effective as the pharmacological ones and should be provided to all patients