DNA Replication Process: Unzipping, Synthesizing, and Joining Strands

Dec 26, 2025

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This overview captures the intricate process of DNA replication, highlighting the roles of key enzymes. The helicase unwinds the DNA double helix, “unzipping” the strands. Primase synthesizes RNA primers necessary for DNA polymerase III to initiate DNA synthesis on both the leading and lagging strands. As the leading strand is built continuously, the lagging strand forms in segments called Okazaki fragments, which are later connected by ligase. This precise orchestration ensures accurate DNA replication, essential for cellular division.

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DNA Replication Process: Unzipping, Synthesizing, and Joining Strands

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